In the future of 3001, after the collapse of civilisation as we know it, when the world has changed not quite beyond recognition, malarial fevers resistant to ordinary quinine will kill thousands.
But in some parts of the world – the mountains near the lake that now covers Portland, Oregon, for example – a cure may be found. That cure is Super Quinine which is found in the leaves of the plentiful rhodeodendrons that grow in that area.
It is generally accepted that these particular rhododendrons, although found growing wild (and only later cultivated) are not naturally occurring, but the result of genetic engineering carried out at some point before the fall of civilisation as we know it, although the exact details of their creation are lost.