The magical dust from the very pouch of the Dream King himself, Dream Sand as a hallucinogen that makes hallucinations real – and makes reality hallucinatory. A user of Dream Sand can mutate the flesh of anyone near enough (and it’s unclear how close that is, although line of sight seems likely), can entrap others in dreams and can prolong their own life far beyond any need for other sustenance (although not without considerable physical wasting – the magic keeps the body alive without them, but the body still needs food and drink).
Fortunately, Dream Sand is kept tightly controlled by the Dream King (whether that be Morpheus or Daniel), and it is only in rare circumstances that any human gets the chance to become addicted to it. The 72 year long imprisonment of the Dream King for the Magus Burgess was such an occasion, unfortunately, claiming the lives of at least two people and very likely more.
Krotan is a potent short term mutagen, which allows complete shape-shifting for the user. It was at one time quite popular amongst the upper classes of Thanagar – although it appears to have also worked for a variety of other alien races.
The primary Krotan dealer on Thanagar was Byth – who was also the head cop, so there was a slight conflict of interest. Eventually, Byth was overthrown and fled to Earth, now hopelessly addicted to Krotan – maddened both by the drug itself (seems his brain never uite made it back to its original shape) and by his subsequent withdrawal from it.
One of the most addictive and dangerous of steroids, Venom first appeared on the streets of Gotham City early in the self-appointed mission of the Batman. In fact, Batman himself was one of its most prominent users for a time.
Unfortunately, in addition to enhancing strength to a superhuman degree, Venom had a number of side-effects, including muscular dystrophy (when not in use) and a capacity to addict users stronger than most drugs short of crack. Batman quickly realised this, and went cold turkey, a process that took about a month (and which was accompanied by incredible physical pain and vivid hallucinations). He never used the drug again, although villains such as Bane and Lex Luthor did.
Related Drugs: Titan.