Adara’s Rose

A somewhat lopsided flower, though pretty and pleasantly-scented in its own way, Adara’s Rose was created by the wizard Belgarion more or less by accident one day in Algaria.

Unbeknownst to Belgarion (or to Adara, for whom he created it), the flower was also capable of being made into a potent medicine – the sovereign remedy, in fact (a cure for all known disease).

However, this second fact was not known until several years later, when it was revealed by the seer Cyradis, and used to cure the Mallorean Emperor ‘Zakath of a bad case of thalot poisoning.

Related Drugs: Athsat.

Agony

Agony, also known as Liquid Pain, is exactly what it claims to be: the distillation of pain and suffering by magical means into a drug. The resulting substance is a thick, reddish liquid resembling blood only more viscous.

It is highly prized among certain extra-planar beings, who can use it to feel pleasures greater than they are otherwise able. Side effects of Agony include an initial stunning effect that incapacitates the user for a brief period and leaves them groggy for a time after that. Curiously, it also makes them more attractive to anyone around them for a period lasting anywhere from one to eight hours.

Agony would likely be a drug of great addiction among demons, devils and their ilk, were it not for the fact that an overdose causes unconsciousness, which means that the effects are wasted instead of the users.

Related Drugs: Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Akkadris

An alchemical preparation usually in the form of a dust, Akkadris is a euphoric and stimulant.

It is highly addictive, causing withdrawal symptoms including profuse sweating and violent mood swings in those who attempt to quit it.

It is also highly illegal, and because it is more commonly a drug of the well-to-do than of those closer to street level, many Akkadris users labour under the dual burdens of addiction… and blackmail.

Akira

A highly addictive drug, Akira is an enhancer of psychic powers. It turns ordinary mortals into psychics, and those who already have magical or psychic talents into virtual superhumans – while it lasts.

The exact details of its naming are unknown, but it seems likely that it was named for the legendary Japanese comic series, which prominently features psychic powers.

Akira enjoyed a brief vogue as the drug of choice of Los Angeles’ Sub Rosa (i.e. magical) subculture, but the strongly expressed disapproval of Sandman Slim (and the disappearance of its source) put paid to that.

Related drugs: Cupbearer’s Elixir.

Allswell

Allswell is a chemical that naturally occurs in the human brain (at least, the humans of Arbre). It makes people feel a sense of well-being and optimism. Some centuries ago, it was genetically engineered into the plant named Blithe, which is a dietary staple throughout Arbre.

Throughout Arbre except in the maths, that is. The avout are forbidden to consume it – or even to grow it – and their time spent outside their maths is limited to ten days in order to stop it from starting to affect them adversely.

Alphanella Seeds

A highly addictive hallucinogen, Alphanella seeds are used by many artists throughout the galaxy – notably the painter Poor Yorick – to help fuel their inspiration. Strangely, despite the popularity of the seeds, little is known of the Alphanella plant, although it is presumably either quick-growing, adaptable to wide range of climes, or both.

The seeds themselves are small and brown, but each of them is quite potent, although the effects tend to wear off quickly. The effects include enhanced senses and cognition, and an unchained imagination. But long term use tends to debilitate the user, leaving them unable to think or talk straight when they are not on the drug.

Higher doses can induce trance-like states that last for several hours, sometimes even days.

Related Drugs: Niathol

Amazo Pills

Little is known about Amazo Pills other than the name. Certain inferences can be be made based on it, however.

Amazo Pills are named after an android created by one Professor Ivo, which was able to duplicate all the superhuman abilities of the Justice League of America.

It is likely, therefore, that the pills duplicate this effect to some extent, and presumably allow the user to duplicate the powers of nearby superhumans. Amazo himself was able to duplicate even powers granted by artifacts such as Green Lantern’s ring or Wonder Woman’s lasso – it is unlikely that the drug is anywhere near this powerful.

Related drugs: Darkshots, Hyperdrene, Mongoose Blood and Xenite

Apprehension of Beauty

Apprehension of Beauty is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

A very, very distracting drug, Apprehension of Beauty is a minor hallucinogen that does not cause visual distortions, but does cause the user to pay more attention to, well, everything. As such, they tend to wander about looking like slack-jawed yokels in the big city for the first time.

Related Drugs: Buzz, California Mello, Funnybone, Get Wired, Pattern Perception, Rhinoceros & Verbality

Ascomycin

One of the most societally destablising drugs ever developed, Ascomycin is an anti-agathic, which is to say, it is a drug that prevents or retards aging.

Ascomycin is a drug that confers non-specific immunity. It’s less an anti-biotic than a true endotoxin, and works to prevent nearly any disease from affecting those dosed with it – and a single dose lasts about 70 years.

The mechanism of the drug involves stimulation of the reticulo-endothelial system (the white blood cells and such). It is apparently a biological drug with multiple sources, though generally not more than one or two to a plant. The Okie ‘Cities in Flight’ use it as part of an their immortality drug suite.

Related drugs: Tricetyltriparanol

Athelas

The herb known as Athelas in the Sindarin tongue is a powerful healing agent when correctly prepared, and a moderately effective one if less correctly prepared. It is common in Middle Earth, especially in those territories that form (or once formed) the kingdoms of Arnon and Gondor, having originally been carried there from Numenor.

For such a useful herb, its properties had been largely forgotten by all except the Dunedain Rangers of the northern wilderness by the end of the Third Age. It was the healing agent of choice for Aragorn, and no doubt was incorporated into the knowledge of Gondor, Rohan and their allies after his ascension to the throne as King Elessar.

In Westron (the tongue of men), its name is translated as Kingsfoil, while in the Elven Quenya language, it is called Asëa Aranion.

Related drugs: Ent-Draughts, Miruvóre and Pipe-Weed

Athsat

Athsat is a potent and deadly poison, which acts quite quickly, causing difficulty in breathing, violent convulsions, and finally, err, death. Unusually, it is harmless unless activated by the victim’s own physical excitement – likely responding to hormonal triggers.

A rare and highly expensive poison, it originates in Nyissa, and is rarely sold to foreigners – and only then at prices that make its regular one seem cheap in comparison.

Related Drugs: Adara’s Rose.

Babbling Beverage

Babbling Beverage is a potion that causes the imbiber to babble nonsense.

As such it is commonly used to play pranks or to undermine authority figures.

Related Drugs: Doxycide, Dr. Ubbly’s Oblivious Unction, Garrotting Gas & Murtlap Essence.

Baccaran

Baccaran is mysterious drug of unknown composition, magical steroid and intelligence enhancer that also renders the user more vulnerable to magical illusions.

Curiously, despite this side effect, it is not actually an hallucinogen, and it is unclear why it has this particular and unusual effect on users. Baccaran is known to be cause great pain if overdosed on, the result of over-stressing the body with its strength enhancing qualities.

Related Drugs: Agony, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Batch 5

Batch 5 is a particular formulation in a series of mixtures of Pituarin and Pinearin. The exact quantities of each, and any other possible ingredients, are not known. A potent and unpredictable mutagen, it was administered to several inmates at the Larkhill Resettlement Camp during 1993.

While the effects of Batches 1 through 4 are unknown, Batch 5 frequently caused the development of supernumary organs in those it was administered to, often accompanied by the atrophy of other organs. It was regarded as a success by the researchers and administration of Larkhill, although those it was administered to were not volunteers and gave no consent to be experimented on, and most of them died in agony.

In at least once case, that of the individual known only as “Codename V”, Batch 5 seems to have caused no deleterious physical effects, instead apparently enhancing strength and agility, although it is possible that the drug did drive “V” mad – or perhaps madder, as “V” may have already been insane at the time he was dosed.

No known samples of Batch 5 or instructions for its preparation survived the destruction of the Larkhill camp by “Codename V”.

Beng Lie

Beng Lie is a powerful suppressant of the will.

It is of Oriental origin, and appears to be a preparation of a variety of drugs and herbs, very likely including opium. Under its effects, users become more submissive, and more receptive to hypnotic and other suggestions, although the very strong-willed can shake off these effects.

Related Drugs: Mei Kuan

Bentlam

Bentlam, also known as benny, ben weed and happy sleep, is am alien drug similar in chemical composition to earthly marijuana. It is, however, prepared to avastly higher degree of purity than any marijuana or hashish or Earth ever was.

In effect, it is a mild euphoric that induces a state of pleasant drowsiness in its users. Other symptoms include impaired physical coordination, although cognition is unaffected. It is illegal in most jurisdictions.

Related Drugs: Fayalin, Hadive, Ladolian, Nitrolabe, Thionite, Vee-Two Gas and VXN Gas.

Bipolar Bears

Bipolar Bears is a line of combination vitamins and mood-altering drugs, produced by The Corporation and marketed primarily at teenage girls. Not much more is known about them, but the odds are that they’re basically chewable Prozac with added vitamin C and artificial orange flavouring.

Black Forest High

Black Forest High is a breed of marijuana grown a woman described (by those who do not know her well, which is nearly everyone) as “a little old lady from Pasadena”. In actuality, the woman in question is more or less ageless. Her name is Agnes, and just by coincidence, she’s a witch. A murderous cannibalistic Nazi witch.

The Black Forest High was grown in the basement of her house, which was extensive as a result of having been originally constructed as a funeral home with a large attached bomb shelter, and fertilised with the remains of the young humans killed by the witch. At the present time, all known samples of Black Forest High have been destroyed, but Agnes is still out there, somewhere. Only time will tell when she returns and whether she’ll bring her drug with her.

Black Frost

An alchemical concoction masquerading as a craft beer, Black Frost was briefly on sale at one particular bar on the Sunnydale campus of the University of California.

Repeated doses of Black Frost will lead to the imbiber reverting to a caveman-like level of intelligence, closely followed by physical mutations to match. Understandably, the user rarely realises that they have been dosed before it’s too late for them to realise much of anything.

It’s mostly used to get even with smart-ass college kids.

Related Drugs: Calendula, Calynthia Powder, Gill Man DNA and Orpheus.

The Black Meat

Made from the sun-dried meat of the giant aquatic Brazilian centipede, the Black Meat is a rare delicacy even among drug users.

Little is known of the giant aquatic Brazilian centipede, and indeed, conventional taxonomies do not list it. It is unclear whether it the insect inhabits freshwater or the seas, although the former is more likely.

The centipedes are harvested by Interzone Inc., and taken to Interzone in North Africa where the flesh is dried by the hot Saharan sun. It is then ground up to form a light black powder, which can be injected or snorted by the user. Its effects are largely undocumented, although one user who was using it mixed with Bug Powder described the experience as ‘a Kafka high’, in reference to his story, Metamorphosis.

Related drugs: Bug Powder, Mugwump Jism and The Drug That Does Not Exist.

Blue Glass

One of the CIA’s “New Ghetto Drugs for ’98” collection, Blue Glass is a cheap upper that comes in the form of a blue powder smoked like crack.

The Onion

The results of taking Blue Glass include almost the complete list of classic euphoric effects: feelings of extreme optimism and happiness; greatly enhanced reflexes; sensory and sexual pleasure; and improved visual acuity.

Sadly the effects are almost immediately followed by the onset semi-permanent suicidal catatonia, meaning that although users will become addicted very quickly, they will also be unlikely to rouse themselves to get a second hit of Blue Glass, despite its low, low price of only a single American dollar per hit.

Related drugs: Brainscratch, Spike and Zom-B.

Blue Mold

The Blue Mold grows wild on the walls of the derelict parts of London’s underground railway network. It’s slightly luminous, but for the real fun to start, you have to smoke it.

Smoked in a pipe, joint or bong, the Blue Mold is a powerful hallucinogenic that unshackles one’s mind from this reality, and allows it to perceive normally invisible parallel dimensions.

It’s used in the initiatory ceremonies of the mysterious conspiracy known as The Invisibles, and possibly in others of their ceremonies as well. In the world of the Invisibles, not only are the words of the prophets writtten on the subway walls, but the source of all their visions grows there free for anyone to take.

Related drugs: Key 17 and Zombie Crack.

Blue Shock

Blue Shock looks like a shiny blue cough syrup and kicks like amyl nitrate’s bigger, stronger brother. Generally taken in doses of no more than a teaspoonful at a time, the immediate result of ingestion is agonising pain.

Fortunately, the pain wears off after a few seconds, leaving every nerve in the body more sensitive than usual. As such, it can be used to heighten sexual pleasure (and it is popular in Al Amarja’s S&M scene for both its effects).

Of course, having your sense of touch heightened also makes pain more intense, so it’s not all good. Not to mention the statistically improbable correlation between Blue Shock use and spontaneous combustion.

Related Drugs: Communion, MDA-Cubed, Nightmare, Relapse, Slo-Mo, Wings and Zorro.

Blue Sunshine

In September 1967, Blue Sunshine was created in a lab at Stanford. It was a variant of LSD, used by a number of members of the graduating class of that year.

In 1978, a previously unknown set of side effects to Blue Sunshine use became apparent: it caused swift hair loss, inhuman strength and murderous psychotic episodes in several users. Medical study of one of them showed severe chromosonal damage resulting from the drug’s use. An investigation conducted by the FDA located some but not all of the former users of the drug, with a total of 255 doses remaining unaccounted for.

Brainscratch

One of the CIA’s “New Ghetto Drugs for ’98” collection, Brainscratch is a cheap hallucinogen that comes in the form of a liquid taken by dropping it into the eyes.

The Onion

The result of taking Brainscratch is terrifying hallucinations. Test subjects reported loss of identity and feelings of total dislocation from human world, and its effects can last anywhere from ten years to the rest of the life of the user. Pretty good value for the cost of only two American dollars per hit.

Related drugs: Blue Glass, Spike and Zom-B.

Bug Powder

A basic insecticide of the fifties in common use throughout New York City, Bug Powder is a yellowish powder that apparently kills bugs.

I say ‘apparently’ because from what little we see of it, it’s none too effective on bugs. Indeed, it is sufficiently un-threatening that it can be eaten or injected by humans, which is hardly the quality of a deadly poison.

It apparently improves the sexual experience, at least for women, with one user stating that she no longer needed to reach orgasm thanks to the drug. Its other effects are not well-known, although one user who was using it mixed with heroin described the experience as ‘a Kafka high’, in reference to his story, Metamorphosis.

Related drugs: The Black Meat, Mugwump Jism and The Drug That Does Not Exist.

Buzz

Buzz is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

Buzz is a low grade stimulant, enough to keep you pleasantly energetic, but not enough to induce teeth grinding, paranoia or other such symptoms.

Related Drugs: Apprehension of Beauty, California Mello, Funnybone, Get Wired, Pattern Perception, Rhinoceros & Verbality

Bynogol

Bynogol was the first drug created by Dr Phillip Wang for Calenture-Deutz. A hayfever treatment, it was retailed in both inhalant and pill forms. It was the drug that made Calenture-Deutz, their first real success.

Bynogol was one of the few drugs to be profitable enough to survive the demise of Calenture-Deutz, and it remains available via Rilke Pharmaceuticals.

Related Drugs: PRO-Vyril and Zembla-4

Ca-Fix

Ca-Fix is a drug of the space age.

It is intended to help treat the effects of spaceflight osteopenia – the phenomenon whereby prolonged exposure to low gravity, micro-gravity or zero gravity environments causes the bones to weaken. It is unclear whether Ca-Fix works to prevent or reduce the loss of calcium, or whether it replaces lost calcium.

Related Drugs: Relaxon

Cake

Cake is a made up drug which is a metabolically bisturbile cranabolic amphetamoid, originating from the Czech Republic. After becoming popular in Prague at so-called “boom raves”, it spread to other European cities, notably London. It is so new that it was technically legal when it first reached the United Kingdom in 1997, in what became known as the ‘summer of death’.

Side effects of Cake include severe water retention, especially in the neck (a symptom referred to as ‘Czech Neck’, which is caused by the yellow dye frequently used to increase the visual appeal of the drug). Another common symptom is massive dehydration, caused by the body expelling the water via tears or vomit. Another effect of Cake, via its active chemical, dimesmeric anson-phosphate, a psychoactive that affects the part of the brain known as Shatner’s Bassoon, which deals with time perception, elongating it massively. Frequent users often experience symptoms of depression.

Cake is also known as “loonytoad quack”, “Joss Ackland’s spunky backpack”, “ponce on the heath”, “rustledust”, or “Hattie Jacques pretentious cheese wog”, and was once the subject of a question in Parliament by MP David Amess (Conservative Party Member for Basildon).

The scourge of Cake has apparently now been defeated, as it has not been sighted on the streets of Europe for well over a decade.

Calendula

Calendula is actually a real substance: it’s a herb derived from the plant of that name. The plant is a small yellow flower that grows across Mediterranean Europe and the Middle East, from the Azores to Iran.

It actually has medicinal effects – it has traditionally been used to treat constipation, abdominal cramps, acne, and in modern eras, radiation dermatitis and tumours. It is also used in cooking.

What lands it on this list is its supposed magical power: it is used by some members of the staff at Wolfram and Hart as a means of cheating psychic scans, by allowing users to hide their true thoughts and feelings.

Related Drugs: Black Frost, Calynthia Powder, Gill Man DNA and Orpheus.

California Mello

California Mello is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

As the name suggests, it provokes a feeling of mellowness in the user, akin to being mildly intoxicated. It is most often used in combination with other drugs.

Related Drugs: Apprehension of Beauty, Buzz, Funnybone, Get Wired, Pattern Perception, Rhinoceros & Verbality

Calynthia Powder

Calynthia Powder is a bright purple colour. As a powder, it can be mixed into liquids and ingested, such as water or blood.

The drug is presumably magical in nature, and is used to affect the dreams of the person being fed it – usually without their knowledge. The drug makes the user more suggestible, especially when in a dream state, allowing anyone present while the user is dreaming to plant suggestions in their mind – while full control is not possible, it can be used to manipulate the person.

A person under the influence of Calynthia Powder will sleep more deeply, which makes the manipulation easier, as they will not wake when they otherwise would. Repeated doses will upset the sleep cycle of the user, making them sleep longer, dream less and awake less refreshed.

Related Drugs: Black Frost, Calendula, Gill Man DNA and Orpheus.

Carvati’s Cure

Carvati’s Cure was created by Dr Carvati of Gehenna, as its name suggests. It is a combination od drug and gene rewrite specifically designed to cure the La’Heng people of the deleterious effects of the RC-12 drug that made them slaves on a genetic level generations earlier.

Although named Carvati’s Cure, the initial research on the drug was carried out by Dr Solaith, and Carvati himself noted that without the genetic records of the Makers (the ancient and apparently long-dead alien race who created the jump point network that allows sppedy interstellar travel), it would have been impossible to complete. The effectiveness of the drug can be seen in that its introduction to La’Heng led directly to a revolution on that world, culminating in the La’Heng people kicking out the other races that had oppressed them and declaring themselves an independent polity.

Related Drugs: Kosh, Rejuvenex and RC-12

Caskan Wolf Snake Venom

Caskan Wolf Snake Venom is a deadly poison to various species on the planet Caska. It is also, curiously, a strong hallucinigen to humans are some other sentients.

As an illegal substance under imperial rule, Caskan Wolf Snake Venom is sometimes smuggled into the Empire’s jurisdiction.

Castran’s Binder

Castran’s Binder is a purgative that is administered in some cases of heavy metal poisoning, particularly those where cadmium or closely related substances are the poisons.

As the name suggests, it is a binding agent, working on a molecular level to capture molecules of the heavy metal and carry them out of the body by the normal processes of elimination. It is known to be safe to administer to humans and Shorshians.

Related drugs: Miccrano, Modhra Coral, Printimpolivre-bioxene, QuixHeal and Saarix-5.

Cerebrocreatine

Originally developed by Banner Value Drug and Vitamin Laboratories, Inc. as a cure for nerve damage, intended to stimulate the growth of damaged nerves, Cerebrocreatine was a failure in that goal, but worked very well in enhancing the development of neural pathways in the brain. Unfortunately, the side effect of these little yellow pills tended to be a fascination with knowledge for its own sake, a penchant for grandiose experimentation and marked tendency towards pednatry.

Cerebrocreatine is one of the few drugs in history to have had its own antidote – marketed as Super-Aktion – developed by the same company that created it, although like Cerebrocreatine, the antidote too was also too strong…

Related Drugs: De-Tox, Nullergin-200 and Super-Aktion

Cernadine

A highly expensive and addictive drug, Cernadine provides a hit that temporarily creates sensations of emotional lassitude and heightened confidence. It is taken as a mild stimulant and euphoric. Unfortunately, the symptoms of coming down include heightened anxiety and lowered self-esteem, which tends to quickly get the user on a treadmill of taking the drug.

While it is legal (at least on the planet Aurore), Cernadine is a dangerous substance to all but the strongest willed. Even with the assistance of a God, overcoming addiction to it is far from easy.

Clarity

Designed for the treatment of Alzheimers, Clarity is a product of Judge Pharmaceuticals. Early animal trials found that it increased cognitive function in rats, but due to the need for secrecy, finding human subjects to test it on proved more difficult.

However the drug’s commercial viability – as a potential cure for Alzheimers, Judge stood to make millions, if not billions – was such that the history of Clarity is one of literal backstabbing – the race for to take credit for it in the company led to murder on more than one occasion.

Cliasmol

A short-lived over the counter drug from the 1990s, Cliasmol was claimed to cure ‘addiction to Pringles’.

The fact that it is no longer sold can be taken as indicating that one or both of the following is true: that Cliasmol was ineffective as a treatment and thus sold poorly once word got around, or that Cliasmol caused deleterious side effects that made its withdrawal from sale a legal necessity. Sadly, in its absence, the scourge of Pringles addiction continues unabated.

Cloveritol

Little is known of the drug Cloveritol, even among medical professionals. While many of them are happy to push it (as a result of the generosity of the company that produces it), its effect on patients remain unclear.

The slogan of Cloveritol is “When life’s not fair at all, use Cloveritol,” suggesting that it may be an upper of some sort, possibly a mood stabiliser, but it’s impossible to say for sure.

Related Drugs: Plomox.

Coltari

Coltari is a deadly poison, used by the Moredhel of Midkemia during their alliance with the Six. It is believed to originate on the world of Kelewan (and carried to Midkemia by Tsurani magicians),

A thin green substance, Coltari is a strong and deadly poison that few beings can withstand. Although the nature of its physical substance is not described, it can be used to envenom weapons, suggesting a viscous liquid. Even Tomas, the reborn Valheru, took several weeks to recover from being shot by such a weapon, and it is surely fatal to any human, elf or dwarf who ingests it.

Related drugs: Joy.

Communion (Dark Heavens)

Communion is a deeply sinister drug, and all the more so for being legal. In a future of ecological catastrophe and over-population, that government has sanctioned mass suicides. They even provide the drug for them, at no charge: Communion.

The drug has two parts: a neurotoxin absorbed through your saliva, and a muscle relaxant that kicks in more slowly, killing you softly and painlessly.

Unless, of course, your mouth is dry from the excitement of your impending end, in which case the neurotoxin won’t work as advertised but the muscle relaxant will, killing you, but only after a minute or so of extreme physical anguish during which time you are fully conscious but unable to move.

Communion (Over The Edge)

Communion is a bitter-tasting powder that causes the user to experience ecstatic union with their god or gods. Usually taken by mixing into tea (generally with a lot of sugar), Communion is particularly popular with the devotees of Karla Sommers living on Al Amarja.

The drug is all-encompassing, affected all five senses. Users often come back from their trips with missions – often vaguely-defined – from their deities. The objective reality of the experience of Communion is a hotly-debated topic in theological and pharmacological circles.

The drug itself is made from the glands of dead glugs, the secretive original species of humans who hide in our midst – although most glugs would be horrified if they knew the drug’s origins, and would almost certainly kill those of their number who are responsible for its creation.

Related Drugs: Blue Shock, MDA-Cubed, Nightmare, Relapse, Slo-Mo, Wings and Zorro.

Confusing Concoction

The Confusing Concoction, also known as Confusing Draught, is a potion which causes confusion in the drinker.

Few details have been revealed regarding it, but it seems unwise that how to make a potion with such potential as a date rape drug was taught to a group of horny teenagers.

Related drugs: Rat Tonic, Shrinking Solution and Wolfsbane Potion.

Cortexin

Created by Dr Michael Grant, a Washington DC based scientist, the original purposes of Cortexin was lost to history – along with its creator and all his notes – when a nuclear war broke out. Grant’s test animals, who had been injected with the drug, escaped in the course of the devastation that followed.

It was at this point that what was presumably an unintended side effect, the animals dosed with Cortexin proved to been altered on a genetic level. Over the course of several generations, they developed greater intelligence, bipedal locomotion, hands with opposable thumbs, and even the power of speech.

A variety of species were used by Grant in his experiments, including apes, bats, dogs, gophers, leopards, lions, pumas, rats, sloths, tigers and wolves. The wide range of species, and the fact that each of them had a large enough population to be able to breed viably, along with the location of Grant’s researches, strongly suggests that his experiments were funded by the Pentagon.

NB: there is no known connection between this Cortexin and the real world drug of the same name.

Cupbearer’s Elixir

Strongly implied to the ambrosia of the gods, the liquid supplied by Hebe to the Olympians that kept them immortal and deific, Cupbearer’s Elixir is an alchemical preparation whose formula is a closely guarded secret.

Despite its general associations, it is not actually a healing elixir. Rather, it halts the changes of the body, retarding injury, disease and healing to an equal degree. While it is often used to halt the spread of incurable diseases, such as leprosy, it can also be used to prevent scars from healing, should one be so inclined.

Related drugs: Akira.

Cuppliance

Compulsory to drink before going on stage to compete in Hot Shot, the actual effects of Cuppliance are not entirely clear. It does seem to affect the judgement of those who take it, making them more vulnerable to badgering by others.

As the name of Cuppliance – a portmanteau of ‘cup’ and ‘compliance’ – implies, it is a vital tool in the maintenance of the status quo in the dystopian future where most episodes of Black Mirror seem to occur, ensuring the vulnerability of the contestants on Hot Shot to the wishes of the judges.

Darkshots

A cyberdrug, that is, one used only by robots and other cybernetic organisms, each Darkshot is in fact part of the body of the entity variously known as the Hell Ditch Pilgrim or Andy Soames.

One of the most potent drugs ever known, each Darkshot is a small captured quantity of Dark Energy – the very virtual particles that bind galazxies and timelines together. Taking it allows machine consciouness to access – or at least view – the root controls of the universe in some fashion.

Perhaps fortunately, Darkshots are no longer produced, as the entity that it derives from has now mutated into a more benign form.

Related drugs: Amazo Pills, Hyperdrene, Mongoose Blood and Xenite

De-Tox

A pale green pill with a potent effect, De-Tox is a product of Banner Value Drug and Vitamin Laboratories, Inc. The recommended dosage of De-Tox is three pills each day at most, and its intended purpose is to counteract the harmful mental effects of pretty much any other drug in existence.

De-Tox does exactly what it says it will, an effect it acheives by stimulating the parts of the brain concerned with logical and critical thought. But a very short time after it came on the market, it was a best-selling drug everywhere and almost every user was exceeding the dosage. This had an unexpected side-effect – over-stimulation of the brain caused it largely shut down after a while, which led to precisely the opposite effects as usual. Fortunately, after a well-publicised scandal involving serious De-Tox addicts, the drug lost popularity and Banner Value Drug and Vitamin Laboratories, Inc. quietly withdrew it from the market.

Related Drugs: Cerebrocreatine, Nullergin-200 and Super-Aktion

Deathsticks

Deathsticks are a serum, usually distributed in glass tubes – to consume, the user simply ingests the contents, which are bright red or yellow in colour (the different colours are purely cosmetic and have no different effects).

Taking Deathsticks is quite popular among a certain class of people living not quite as long a time ago in a galaxy far, far away: among other effects, it deadens the user’s connection to the Force, which can be desirable to those who want no part of the endless Sith-Jedi struggles.

It is a potent hallucination, which makes it easier to dismiss any Force-ghosts one might see as mere hallucinations. As the name suggests, however, taking it tends to shorten one’s lifespan not inconsiderably.

Deflating Draught

The Deflating Draught is probably best known as an antidote to the Swelling Solution. As such, it is a standard medical treatment in the wizarding world, used to reduce swellings of all kinds, whether they are magically induced or not.

Rumours that it can be used as a kind of magical viagra remain unconfirmed.

Related Drugs: Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.

Devilweed

Devilweed is made from the leaves from the wyssin plant, which are dried and
rolled into a tobacco-like substance and smoked, although they can be taken in other ways also.

Although native to worlds where magic is common, Devilweed is not itself magical, and appears to be local equivalent of marijuana in these worlds.

Related Drugs: Agony, Baccaran, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Diarrax

Diarrax is a medical grade laxative that enjoyed a brief vogue in the mid-nineties United Kingdom, where it appeared on the scene just as the privatisation of the NHS really got going.

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Diarrax would not be noteworthy at all except for its tangential connection to one of the worst scandals in Scottish medical history: a symposium on euthanasia it sponsored for the Midlothian NHS Trust, at which the head of the trust, Stephen Lime, recruited one Dr Jeremy Ponsonby to serve as a provider of involuntary euthanasia to several patients in the Trust’s geriatric facility.

It is believed that the resulting bad publicity may have tainted the brand, as Diarrax is no longer in common use in NHS facilities.

Dilligenz

A drug that makes it possible to work even harder would only ever be popular in one place: the Action Center, where people have been known to have their need for sleep surgically removed. Technically, Dilligenz is illegal, but since a cabal of its users informally seized power in the Action Centre, that’s more or less a moot point.

The real problem with Dilligenz is that it’s made from the brains of other human beings. The process is as painless as anything involving a syringe can be, but tends to leave the ‘donor’ rather docile. As bad a crime against humanity that is, Dilligenz II is worse: a stronger version of the drug, it tends to leave its ‘donors’ in persistent vegetative states. Which is why none of them are volunteers.

Or not.

Actually, all of the above is a story put about for political reasons connected to maneuverings inside the Action Centre. In truth, Dilligenz is manufactured from a plant extract, and what limited effects it has are placebos.

Related Drugs: Dopaz, Jahavan coffee and Strim

Dr. Ubbly’s Oblivious Unction

Dr. Ubbly’s Oblivious Unction is a curative potion used to treat the psychic wounds left by telepathic and other mental attacks.

It is not a complete cure, requiring repeated applications over a long period of time, and even then, some scars may remain.

Related Drugs: Babbling Beverage, Doxycide, Garrotting Gas & Murtlap Essence.

Dopaz

An hallucinogen of such terrifying potency that they use Crack to cut it, Dopaz is regarded as a terrible drug even by those who take Strim.

The overwhelming sensations of taking it are a powerful lethargy, and an equally (if not more) powerful obsession with the colour orange. To the Dopaz user, all knowledge, truth and wisdom in this world is to be found in the colour orange, but since you have to be on Dopaz to really understand this, the revelations have been understandably slow to spread.

Related Drugs: Dilligenz, Jahavan coffee and Strim

Doxycide

Doxycide is a powerful black potion with a foul odour, which, when sprayed on Doxies, causes them to fall into a state of paralysis for a time.

The name of Doxycide is misleading, as it does not directly kill Doxies. It does, however, leave them in a state that frequently leads to their deaths.

Related Drugs: Babbling Beverage, Dr. Ubbly’s Oblivious Unction, Garrotting Gas & Murtlap Essence.

Dream

Dream, also known as Bliss, is an addictive narcotic sold by assorted drug dealers in the world of Midkemia.

The few users that are mentioned are all whores, and it’s possible that Dream is provided to them by their pimps to keep them addicted and willing to work. The drug’s hallucinogenic properties provide an escape from the crushing reality of their lives (as whores working from brutal criminals in a world with medieval technology), but the need to pay for it embeds them further into these lives. It is a deeply unpleasant situation, and more than one such user of Dream has committed suicide.

Dreamgum

Created by the Ethicals of the Riverworld, Dreamgum is a form of highly addictive chewing gum. It is distributed along with their food to all Riverworlders at each evening meal in their Grails.

It causes vivid hallucinations and a certain degree of lowered inhibitions amongst users. Since the first time it was distributed no one knew what its effects were, the first night on Riverworld was an orgy of sex and violence.

After that, it became a much less popular drug, although a certain number of Riverworlders became hardcore addicts – an addiction that could not be broken by the death and resurrection, as it has no physical component.

Dream Sand

The magical dust from the very pouch of the Dream King himself, Dream Sand as a hallucinogen that makes hallucinations real – and makes reality hallucinatory. A user of Dream Sand can mutate the flesh of anyone near enough (and it’s unclear how close that is, although line of sight seems likely), can entrap others in dreams and can prolong their own life far beyond any need for other sustenance (although not without considerable physical wasting – the magic keeps the body alive without them, but the body still needs food and drink).

Fortunately, Dream Sand is kept tightly controlled by the Dream King (whether that be Morpheus or Daniel), and it is only in rare circumstances that any human gets the chance to become addicted to it. The 72 year long imprisonment of the Dream King for the Magus Burgess was such an occasion, unfortunately, claiming the lives of at least two people and very likely more.

Dreamsmoke

Little has been revealed of Dreamsmoke, other than that it is smoked (as the name suggests) and that smoke leaves a pungent scent behind afterwards.

Based on contextual clues, Dreamsmoke is probably a name for a strain of marijuana, and, given the nature of the world in which it exists, likely a magically enhanced one.

The Drug that does not exist

There is no drug more pernicious or addicting than this. Fortunately, there is also no drug more rare or hard to find. In fact, you can only find it in the movie version of Naked Lunch.

The Drug That Does Not Exist appears to be a creation of the fevered imagination of withdrawing multiply-addicted writer William Lee. God only knows what he was addicted to at that point – Bug Powder, Mugwump Jism, the Black Meat, and possibly even some real drugs like heroin or morphine…

For obvious reasons, little is known about this drug. But the smart money says that William Lee is right, and that withdrawal from it is a real bitch…

After all, if a man as experienced in the matters of addiction and withdrawal as William Lee is absolutely terrified of this particular withdrawal above all others, then it’s something the rest of us are better off not knowing too much about.

Related drugs: The Black Meat, Bug Powder and Mugwump Jism.

Dust

A street drug developed by the very people who are charged with policing it, Dust is a red powder that stimulates telepathic powers in humans (and some other species) for the duration of its use.

Dust was created by the Psi-Corps in an effort to create more human telepaths. It has been an unmitigated failure in that respect, and remains potentially a huge embarassment to the Psi-Corps should its origins become public. In the meantime, the same people who created the drug have the job of hunting down and punishing those who use it.

The fact that the drug works on non-human races, notably the Narn, is most likely indicative of the genetic meddling of the Vorlons with these races, with the drug tapping the telepathic genes implanted by that race.

Related drugs: Psi-blockers

Dyziplen

Dyziplen is the trade name of the behaviour-modifying drug Nitrosedaticam Dedehydro Epoxy Methylmorphixan Diacectate Calminhydrate. Sold in the form of 400mg capsules, Dyziplen is the latest and most fashionable treatment for misbehaving children among the wealthy trophy wives of Manhattan. It is the go-to treatment for hyperactivity, ADHD and Kanye West Spectrum Disorder. It’s not handed out as the treatment for a particular diagnosis, but just for kids who are, you know, inconveniently behaving like kids.

Dyziplen takes a little while to kick in, but once it does, it turns the user into a polite, well-spoken, emotionless, slow-moving automaton who is incapable of recognising music or colour. It’s very likely that a certain amount of bribery caused this dangerously strong chemical to be fast-tracked through the approvals process by the FDA.

Elixir of Life

The Elixir of Life is a potion that prevents aging, although regular drafts of it must be taken or it will wear off. It can also be used in certain circumstances to recreate a body for those who have misplaced theirs through poorly applied magic.

Created by the alchemist Nicholas Flamel through the use of the Philosopher’s Stone, it is unclear whether or not there remains another means of creating it now that the Stone has been destroyed, or whether the remaining supplies of it are all there is.

Related Drugs: Fire Protection Potion and Weedosoros

Ent-Draughts

It’s somewhat unclear whether Ent-Draughts are some form of enchanted juice or some form of enchanted water. Certainly it is loved by Ents, as Treebeard keeps a supply laid in. But what is most attention-grabbing about this liquid the effect that it has on hobbits.

Even a single draught will cause feelings of extreme well-being and act as a restorative to good health and boundless energy.

In the cases of Merry and Pippin, it even caused them to grow a considerable amount, making them two of the tallest hobbits ever. Presumably, it would have analogous effects on humans, although thiis has never been tested – and the only species to drink Ent-Draughts are the Ents themselves. The effect it has on them is unclear, although it is implied to be a mild intoxicant.

Related drugs: Athelas, Miruvóre and Pipe-Weed

Eucharist

The true nature and origin of Eucharist is a closely guarded secret in the Empire of Golgoth. In fact, only he (and a few lieutenants whose curiosity exceeded their loyalty) know how the drug is made.

Eucharist is a highly addictive stimulant (possibly even at mutagenic levels) and euphoric, described by its users as better than sex (although not, apparently, better than sex and Eucharist combined), although its effects wear off in time. Golgoth gives it only to his most trusted inner circle as a means of both empowering them and ensuring their loyalty – and even then, only once a month. It is generally in the form of standard sized capsules, red and white in colour. It is unclear if anyone has ever survived withdrawal from it, but it is widely agreed that going cold turky from it is a terrible physical and emotional ordeal.

The true secret of Eucharist is perhaps the only thing about it that is more horrific than withdrawing from it would be: it is in fact the unprocessed blood of an alien superhero named Endymion, who came to Earth with powers and abilities far beyond those of mortal men… and who was defeated, imprisoned and used as a source of Eucharist by Golgoth.

Euphorazine

A product of Natural Life Food Company, Euphorazine is an anti-depressant that replaced Zanotab when that drug was withdrawn from sale.

It is unclear how effective it is, but many former users of Zanotab are now using Euphorazine.

Related Drugs: Profillica, Teamocil & Zanotab.

Ex-Tend

Ex-Tend is an anti-agathic about which little is known. It appears to be a close relative of the drug FOREVER.

Although little is known about the mechanisms by which it works, it is known that it does not confer actual immortality, in addition to which there were claims of deleterious side effects. Nonetheless, most users are content to take it for now, and let it delay their aging until an even better anti-agathic is invented.

Ex-Tend exists in only a handful of closely-related alternate timelines or eigenstates.

Related Drugs: FEMFREE, FOREVER, NEURO and ORGASMOR

Fast-Penta

An almost completely reliable truth serum, Fast-penta is a commonly-used tool of ImpSec, the Barrayaran intelligence agency, and of numerous of its allies and enemies, too.

The drug itself relaxes physical tensions, as well as mental and emotional inhibitions. It is not so much that it compels honesty, as that it compels docility and helpfulness – which, in the hands of a skilled interrogator, amounts to about the same thing.

Artificial immunity to it is sometimes given to operatives by their agencies, and similar immunity has been bred into the genetically manipulated haut and ba classes of Cetaganda. More rarely, some people have naturally idiosyncratic reactions to it, in which the effects are more similar to those of ecstasy or LSD – Miles Naismith Vorkosigan is one of these.

Related drugs: Synergine

Fastlife

Fastlife is an all-natural, legal stimulant created by Quint Herbal Supplements, with extensive R&D support from elements of Earnshaw Pharmaceutical. Unfortunately for everyone involved, it turned out that Fastlife caused heart attacks among some users, which led to a court case directed against Quint, the founder of the company bearing his name.

Earnshaw’s money tried to keep this killing drug on the shelves, but the involvement of the Leverage Consulting and Associates team managed to defeat them.

Related Drugs: Vioplex

Fayalin

Fayalin is a naturally occurring drug found in the fruit of a native Crevenian shrub. The drug, when extracted from the fruit, is usually drunk in tea, and has a red colour.

It is a mild stimulant with no intoxicating effects, and is considered a luxury item in many parts of the galaxy. Its consumption is often ritualised, and it is somewhat addictive.

Related Drugs:: Bentlam, Ladolian, Hadive, Nitrolabe, Thionite, Vee-Two Gas and VXN Gas.

FEMFREE

FEMFREE is a drug that suppresses the maternal instincts in women. It is not clear how this physical effect is acheived, but it seems likely that it suppresses certain hormones, and likely also reduces the likelihood of conception.

However, the social effects of the drug are even more striking. Shortly after the drug’s introduction, it was outlawed by President Lousewart, which swiflty led to the formation of a black market selling FEMFREE to the women who wanted it.

Related drugs: Ex-Tend, FOREVER, NEURO and ORGASMOR.

Fever

A brutally strong drug, Fever was created in Mexico and imported to Gotham City by the crime-lord known as the Ventriloquist. It had a brief vogue on the streets of that city, but a combination of heightened security at the US-Mexico border and the intervention of the Batman soon brought that to and end.

Effects of Fever include a burning sensation, as if the user is on fire, although this is reported as being an enjoyable feeling. In addition, it removes inhibitions and shortens tempers, while also leading to somewhat megalomaniacal behaviour. In this, it resembles a stronger form of PCP, along with the maniacal self-confidence common to cocaine use.

Fijana

One of the deadliest poisons known to the world of the two moons, fijana is particularly popular among the Asharites, and has been used on more than one occasion in political assassinations, the best known of which was the killing of King Almalik of Cartada, the last Lion of Al-Rassan by Ammar ibn-Khairan and his own son, Prince Almalik.

fijana is a subtle poison with no strong flavour, administered either orally or to the bloodstream for a quicker effect. When ingested, it causes a congestion of the blood vessels, leading to the throat of the victim swelling shut only seconds before heart failure results in death. fijana is, thankfully, rare and expensive.

Fire Protection Potion

Fire Protection Potion – also known as Ice Potion – is a potion that protects the imbiber from the effects of naked flames, whether natural or magical. It is generally purple or black in colour, and known ingredients of the potion include bursting mushrooms, salamander blood and wartcap powder, although it is clear that there are other ingredients in addition to these.

When drunk, Fire Protection Potion gives the imbiber intense chills, sometimes described as feeling like ice flooding their body. Its effects are relatively short lived, but near to absolute while they last.

Related Drugs: Elixir of life and Weedosoros

The Fix

Not technically a drug, but rather a synthetic genetic cocktail designed to be taken by pregnant mothers to reduce pre-natal problems and grant immunity to several childhood diseases, The Fix is a small grey pill, shaped like two cones joined at their wider ends, and resembling more than anything else a weight from a fishing line (without the hole for the line).

Although it is not actually compulsory for pregnant mothers to take, a few decades from now, it might as well be. There are exemptions, but they mostly involve religious grounds. And in the highly regulated future from which it originates, refusal to take the damned thing without a good reason (and it should be noted that the vast majority of so-called good reasons are actually irretrievable irrantionality that the government apparently hopes to breed out of the population over the next few generations) will make the pregnant woman in question the target of all manner of government intervention.

All for the good of the unborn child, of course. Because someone has to think about the children.

Flects

Glass-like shards that are the remains of windows and glassware from cities that have been destroyed by Chaos far in the grim dark future of Warhammer 40,000, Flects are powerfully addictive hallucinogens. Gazing into them causes visions, although repeated use seems to trigger mutagenic effects as well.

Flects are profoundly illegal in the Imperium. The Inquisition ceaselessly hunts both those who use and those who sell the drug, and not without good reason: the visions and mutations are gifts of Chaos, and Chaos does not give gifts for any reason other than to advance the cause of Chaos.

Focusyn

Focusyn is an experimental drug that has effects like a stronger version of Ritalin, sometimes prescribed to particularly severe cases of Attention deficit hyperactivity disorder.

It has a number of effects, including improved curiosity and mental focus, both of which make the user a better student. It also, peculiarly, makes them more polite, which may be a side effect of the increased empathy.

However, Focusyn has a perceived negative effect as well: it is often seen as making the user somewhat paranoid, and prone to imagining baroque conspiracies. One such case was Bartholemew Simpson of Springvale, who believed he had detected spy satellites operated by Major League Baseball after taking a much higher than recommended dose of Focusyn. Simpson was quickly weaned off the drug due to his paranoia, regardless of the fact that he was in fact not paranoid – he succeeded in shooting down one of the actual satellites, suggesting that his paranoia was actually a view of reality that was more accurate than most people’s.

FOREVER

FOREVER is an anti-aging drug produced by Blue Sky Inc.

Although little is known about the mechanisms by which it works, it is known that it does not confer immortality. It is available only in pull form and must be taken daily.

FOREVER is known to exist in most of a cluster of closely-related alternate timelines or eigenstates.

Ex-Tend, FEMFREE, NEURO and ORGASMOR.

Forever Compound

The Forever Compund is an alchemical serum produced by the Brotherhood of the Shield. It is a diluted form of the Elixir of Immortality developed by Isaac Newton in 1652.

While it still retains the life-prolonging properties of its parent elixir, it doesn’t keep any of the other properties. In particular, it does not prevent the mind or body of the person injected with it from decaying.

Newton administered it to Nostradamus in 1652, which kept the seer alive and also kept his prophetic gifts intact until Nostradamus took the Elixir of Immortality three hundred years later.

Friends

Friends are a series of slightly varying stimulants, created by the biochemist Gail in post-pandemic Melbourne, Australia. They’re a slow release amphetamine, peaking several hours after they are taken.

Different versions of the recipe appear to differ in their level of intoxicating power, although all types of Friends seem to have at least some effect in this direction. The drug is mildly addictive and absolutely illegal under the near-theocracy that is post-pandemic Australia’s Nation First government, but is for some reason produced in capsule form and sold in blister packs like aspirin.

Funnybone

Funnybone is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

Funnybone is a euphoric intoxicant, a drug that makes you laugh at almost anything.

Related Drugs: Apprehension of Beauty, Buzz, California Mello, Get Wired, Pattern Perception, Rhinoceros & Verbality

FX7

FX7 is an extremely powerful mutagen, created by Carrick Masterson by extensively by modifying the psychedelic Tryptamine 5-MEO-DIPT in San Francisco in the mid- to late Sixties. He created it as a way to form his own superhuman group, originally called the Levellers, later re-named the Front Line.

However, the effects of FX7 vary wildly from person to person – Masterson refers to the process as ‘tuning’, and even the doses and methods of administration vary based on each subject’s medical work up. Although only one dose is required, to actually make it kick in takes a high level of adrenalin response: a shock or fright. When that happens, the subject can expect 12 hours of horribly mutating pain, after which they will wake up with superpowers.

Gamedone

Gamedone was introduced to the market following the end of the fourth season of HBO’s “Game of Thrones” to help viewers deal with their withdrawal from the show.

Produced by The Wil Wheaton Project, Gamedone blocks the part of your brain that appreciates quality television, and reduces symptoms such as compulsive re-watching, crossbow murder and the urge to see loved ones die. Gamedone is available in capsule form, and is guaranteed to make you feel like a king (a still-living king, not one of the many dead ones who have featured in “Game of Thrones“).

Garrotting Gas

Garrotting Gas is a colourless vapor arising from a potion. It is unclear whether the gas is dangerous to breathe, but it can be deadly nonetheless.

The gas lives up to its name, actually strangling those who pass through it, causing choking and even complete suffocation if exposure goes on long enough.

Related Drugs: Babbling Beverage, Doxycide, Dr. Ubbly’s Oblivious Unction & Murtlap Essence.

Get Wired

Get Wired is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

A potent stimulant that is a great party drug, but probably not so good in any other context, Get Wired isn’t the most popular of Chapman’s output, but it’s probably the most fun.

Related Drugs: Apprehension of Beauty, Buzz, California Mello, Funnybone, Pattern Perception, Rhinoceros & Verbality

Giagra

Giagra was sold through classified ads in some of the more dubious porn magazines. It was a penis enlarging drug that not only lacked FDA approval but actually boasted about the fact in its advertisements. Unsurprisingly, this led the FDA to raid the headquarters of Dopecom, manufacturers of Giagra, and shut them down.

The recommended dose is a quarter ounce a day. Exceeding the recommended daily dose of Giagra can cause side effects such as heart palpitations and blurred vision. A young man named Richard Head broke into the Dopeco factory and was mutated into a human-sized and -shaped penis capable of ejaculating through the hole on the top of his head after falling into a vat of Giagra. He became a supervillain under the name Dick Head.

Gigglepig

Gigglepig is a variant form of ecstasy that experienced a brief vogue as the party drug du jour in Brooklyn in the second half of 2014.

Due the efforts of a New York Police Department task force headed by detective Rosa Diaz of the Ninety-Ninth Precinct, the pipeline smuggling the drug into the city was shut down, and the remaining street supplies of Gigglepig were consumed or abandoned shortly thereafter.

Related Drugs: Turgidol and Taxi

Gill Man DNA

Gill Man DNA is a powerful mutagen that is incorrectly believed by its creator to be a steroid.

Ingested in the form of steam, Gill Man DNA is derived from mutated fish DNA, itself engineered from several different fish species and then further warped by exposure to the magical energies of the Sunnydale Hellmouth.

Although it does increase the swimming abilities of those who take it, the manner in which this is achieved is by slowly mutating them into amphibious fishlike humanoids (it is not clear whether they can breathe underwater as well as in the open air).

Related Drugs: Black Frost, Calendula, Calynthia Powder and Orpheus.

Hadive

Hadive originates on the planet Vandemar, where it is pronounced “hah-DEE-vay”. In most of the galaxy, it is more commonly pronounced “hay-DIVE”. It is a thick black tar not unlike hashish in appearance and texture, and is usually consumed by smoking it in a similar fashion to hashish.

Hadive causes synaesthetic effects in users, causing users to taste sounds or smell words. Organised Hadive dens usually attempt to provoke the strongest stimulus possible, as the intensity of the drug’s effect is directly proportional to the strength of the stimulus. Loud, discordant music and strobing lights tend to feature heavily.

Most users report the synaesthesia to be pleasurable.

Related Drugs: Bentlam, Fayalin, Ladolian, Nitrolabe, Thionite, Vee-Two Gas and VXN Gas.

Hair-Raising Potion

Few details are known about Hair-Raising Potion. As the name suggests, the potion causes the imbiber’s hair to stand on end. That’s about it.

Oh, and one of the ingredients is an unspecified number of rat tails. No one knows why, and we’re all happier that way.

Much happier.

Related Drugs: Deflating Draught, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.

Hemaflexin

Hemaflexin is medical treatment that improves the solubility of blood gasses by manipulating the effectiveness of red blood cells.

A quick-acting drug, the effects of Hemaflexin are felt within two minutes of application. Among other uses, it is good for reducing the effects of the bends (decompression sickness).

Human Drug I

A pill produced on the island of Krakoa, the independent mutant nation located in the west Pacific, Human Drug I is a non-specific, adaptive antibiotic.

It is a naturally produced chemical grown by specialised and unique plants on Krakoa, and distributed to nations that have the appropriate treaties with Krakoa by the Hellfire Trading Company.

Related drugs: Human Drug L and Human Drug M

Human Drug L

A pill produced on the island of Krakoa, the independent mutant nation located in the west Pacific, Human Drug I is a life extension treatment, prolonging human life by five years. It is unclear whether this means five years per dose, or is a singular effect that a given person can only benefit from once.

It is a naturally produced chemical grown by specialised and unique plants on Krakoa, and distributed to nations that have the appropriate treaties with Krakoa by the Hellfire Trading Company.

Related drugs: Human Drug I and Human Drug M

Human Drug M

A pill produced on the island of Krakoa, the independent mutant nation located in the west Pacific, Human Drug I is a cure for ‘diseases of the mind.’ It is unclear whether mutantphobia is one of the affected diseases.

It is a naturally produced chemical grown by specialised and unique plants on Krakoa, and distributed to nations that have the appropriate treaties with Krakoa by the Hellfire Trading Company.

Related drugs: Human Drug I and Human Drug L

Hyperdrene

Of unknown derivation, Hyperdrene is generally considered to be an hallucinogen, as the imps and pixies one sees under its influence are presumably hallucinations.

However, these hallucinations can be seen by other people too, although only during the 4-5 hours that the drug’s effects last, which begs the question of whether or not they are real.

It is possible that Hyperdrene is not an hallucinogen at all, but rather a drug that creates a briefly existing super-position between this dimension and the adjacent one more usually inhabited by the pixies. Attempts to question the pixies about this have been fruitless, as their only form of communication appears to be reciting nonsensical couplets.

Related drugs: Darkshots, Mongoose Blood and Xenite

Hyderdroxipine

A long-lasting hallucinogen that is extracted from a fungus growing only on beaver pelts, Hyderdroxipine is more obscure now than it once was.

When the American frontier was still wide open, and fur traders and trappers were among the first to explore its wilds, Hyderdroxipine was better known (although not under that name – the names given to it by trappers and traders are unfortunately lost to history). However, as the demand for beaver pelts diminished, so too did the availability of the drug.

Potentially deadly in its effect, Hyderdroxipine was extracted only after the removal of its source fungus from the beaver pelt, which usually caused the fungus to become impregnated with the prussic acid used for the job. In addition, the half-life of the drug is said to be 72 hours, and only the most strong-willed of individuals are able to function well while on it. Even Batman found it difficult.

Icpathua

Icpathua is a sedative created from a plant that grows naturally in wherever it is that the true human beings (not vodsels like you and I) come from. Like most matters regarding the human beings, it is shrouded in mystery.

It appears to be a mild euphoric when consumed by human beings directly from the plant, but can also be refined into a strong sedative that knocks out even the strongest vodsel males. In the latter capacity, it was used as part of an extensive hunting operation in eastern Scotland, to capture vodsels for their meat, which is considered a delicacy by human beings, and shipped back to their home to be sold at extortionate prices.

Immobilo

Developed by Control as yet another weapon in the battle for the safety of the free world, Immobilo is a colourless liquid. Administered by injection, it causes paralysis in the user for approximately 30 seconds, and also prevents the formation of memories during this time.

Immobilo will affect most body types normally, but certain amino chemicals in peaches counteract its effects – if one has eaten a peach, one is immune to the drug’s effects for several hours thereafter.

Incredulox

Sometimes employed by Larry Wilmore when stories get too hard to believe, Incredulox is an over the counter medication intended to make the implausible go down easy. (Ironically, the drug itself can be hard to swallow.)

The rather clumsy slogan of Incredulox is: “for when you simply cannot believe it, and it’s true, and you still can’t believe it.” This is one of the few run-on sentences ever to actually make it through the approvals process and actually get used as a slogan. The makers of Incredulox appear to have skimped on focus group spending.

The actual effectiveness of Incredulox is unclear, since it appears necessary to take very large doses in some cases.

Insuleze

Insuleze is a treatment for Type 2 Diabetes produced by the American company Nexachem.

It was given exposure in the USA when it appeared on an episode of Oprah. It is taken in pill form once a week, and reduces the symptoms of bloating. In fact, it seems to be more useful as a weight-loss drug than as a treatment for diabetes.

After a minor media controversy in Australia, the government there agreed to a one year trial period for the drug. The results of the trial have not been made public.

Iocane

Iocane is one of the deadliest known poisons. It is usually found in a powdered form, and dissolves instantly in most liquids. It has no taste or smell, and is thus close to undetectable. It is also a very swift acting poison, killing in less than a minute.

Despite its deadliness, it is possible, by repeated application of the smallest doses, gradually increasing in size over a course of several years, to develop an immunity to it, although the limits of this immunity have rarely been tested, as only a single individual is known to have developed it.

Iocane originates in Australia, where it is a small but highly valuable part of that nation’s export trade, and a well-known tool of business in its criminal underworld.

Jahavan coffee

One of the most potent varieties of coffee yet invented, Jahavan coffee is genetically engineered to race through your bloodstream in search of alcohol molecules, and beat the crap out of any it finds. A single cup will sober you up from any quantity of booze short of alcohol poisoning (and possibly even then).

This tends to cause a level of sobriety closely resembling knurd, leading to foolish and unhelpful thoughts regarding the things in one’s life that usually don’t bother you, like not liking your job, and having no girlfriend, and the galloping menace of tooth decay, and how much everything costs these days, and that stain on the carpet you never noticed before, and…

Related Drugs: Dilligenz, Dopaz and Strim

Joy

A common drug among the poorer citizens of the Empire of Great Kesh, on the world of Midkemia, Joy is a strong euphoric, commonly found in powdered form.

A small amount of Joy, which is usually taken mixed with water or wine, is sufficient for a night’s euphoria. A not much larger dose could reduce the user to a blissed-out stupor lasting days, and in sufficient quantities, it will simply render the user unconscious until it leaves their system.

It is sometimes transported in a more concentrated form, a yellow powder called Heart of Joy that is worth around a thousand times the street value of Joy.

Related drugs: Coltari.

Joyvetrex

Produced by Futurza – the same pharmaceutical company that brought the world both Fibromyalgia, and a highly-priced (not to mention dubiously effective) cure for Fibromyalgia – Joyvetrex was a 2013 anti-depressant and mood enhancer that was heavily pushed onto the medical community.

It is chiefly notable for living up to none of the promises made in its advertising (or by its sales reps).

Related drugs: Mega-Dope and Relaxorex.

Jumpstart

A bog-standard amphetamine with a cool name, Jumpstart is one of the most popular stimulants in the City. It’s even legal for some professions, such as journalists.

Jumpstart is often accused of being an halluncinogen, but in fact, the waking dreams and delusions associated with prolonged use are the normal effect of days or weeks of sleep deprivation, and only incidentally associated with the drug itself.

Related Drugs: Mechanics, Space and Tripwire 7.0.

Key 17

Key 17 is a potent hallucinogen with highly specialised effects.

It causes the user to experience written signals as the objects themselves – a coffee mug reading ‘world’s greatest dad’ would be perceived as the user’s father, for example.

Key 17 is used as a means of interrogation by the agents of the Outer Church, who use it to substitute for actual torture by creating the illusion that such torture has taken place. Key 17 also appears to have a secondary effect (common to hallucinogens in general) of messing with the user’s sense of time’s passage.

A similar drug called Key 23 also exists – it appears to be a later refinement of of the original.

Related drugs: Blue Mold, Sky and Zombie Crack.

Kick

Kick is the street name of the drug Hypercortisone D – but it’s really a sentient bacterium that more often goes by the name Sublime.

Native to the Marvel Universe, Kick appears to cause psychosis, but this is actually the result of it enabling Sublime to control the minds of whoever takes it – a list which includes Kid Omega, Beast and Magneto (or possibly Xorn – accounts vary). In at least one alternate future, this drug/entity actually succeeded in taking over the world, which is a rare accomplishment for any drug to claim.

Sublime/Kick has few discernable goals, but one of them is the absolute destruction of mutantkind, which it regards as one of the few threats to its existence – largely because it can control mutants only when they take it in Kick, rather than the purely viral control that is sufficient to control most humans.

Kosh

An extremely expensive and addictive concoction of mostly natural herbs, Kosh is the foremost pleasure drug sold on Gehenna (or more accurately, on the station of the same name that floats in the atmosphere of that gas giant). It is rumoured to be the most intense pleasure drug, providing what was once described as the “penultimate pleasure” – a level of pleasure so high as to be just barely short of fatal.

Fortunately for the universe at large, the drug lords of Gehenna jealously protect its formula and prevent its export with unmistakable (and usually life-ending) firmness.

Related Drugs: Carvati’s Cure, RC-12 and Rejuvenex

K-Pop

K-Pop is a variant of Ecstasy, which also combines certain features of Adderall. It was created by Sandra June Jang, a high school chemistry teacher who supplemented her income by cooking drugs for the Korean Power gang.

It is a great high, making the skin of the user feel like it is being stroked by chinchilla fur. June was killed and the Korean Power gang was put out of business, at least temporarily – the head of the gang has a copy of her recipe, and when he finally gets out of prison, he plans to go back to dealing K-Pop right across Los Angeles.

Krotan

Krotan is a potent short term mutagen, which allows complete shape-shifting for the user. It was at one time quite popular amongst the upper classes of Thanagar – although it appears to have also worked for a variety of other alien races.

The primary Krotan dealer on Thanagar was Byth – who was also the head cop, so there was a slight conflict of interest. Eventually, Byth was overthrown and fled to Earth, now hopelessly addicted to Krotan – maddened both by the drug itself (seems his brain never uite made it back to its original shape) and by his subsequent withdrawal from it.

KT-28’s

KT-28’s, or Katies, as they are known on the street, are a psychoactive drug from the graphic novel Watchmen by Alan Moore and Dave Gibbons. The effects of this drug are never made clear in the book, only that it is a popular and addictive street drug with the ‘Knot-Tops’ of New York – a curious coincidence, given the drug’s name.

However, in an apparently unrelated section of the book, Dr Manhattan mentions that he can synthesize lithium in limitless amounts, leading to a number of scientific advances based on cheap, abundant lithium.

On that basis, it is likely that this otherwise unknown drug is also a lithium derivative – and indeed, lithium has a long history as a drug used in psychiatric treatments, making it a likely choice. Based on the name of the drug, which sounds more like an abbreviated chemical formula than anything street, it’s likely that KT-28 is a drug with a legitimate psychiatric use that finds its way to the streets illicitly.

Ladolian

Ladolian is a potent hallucinogen that originally derives from the now-gone civilisation of Mars. It is extracted from a species of Martian mold that has long since been exported to every ecosystem that will support it.

In colour, it is a yellow-green viscous liquid, with a distinctive smell and a surpassingly bitter taste. Users often dilute it with ice water, licorice or fennel to cut the flavour enough that it is pleasant to taste.

The hallucinations caused by the drug are usually wish-fulfilment visions, and the drug in perversely popular among the idle rich despite its illegality. Prolonged use leads to a number of unpleasant side effects, most prominently sterility and impaired mental function.

Related Drugs: Bentlam, Fayalin, Hadive, Nitrolabe, Thionite, Vee-Two Gas and VXN Gas.

Lazopril

Invented by 12 year old evil genius Oliver Watson (when he was much younger), Lazopril is a drug with a number of effects, including sudden uncontrollable flatulence and a rapid diminution of levels of hostility and motivation in those dosed with it. Watson has equipped his bodyguards with it, and they generally shoot it into those he designates in the form of tiny darts.

Unfortunately for Oliver, Lazopril also delays the beginning of one’s adolescent growth spurt by about three months for each dose – something Oliver only realised after mixing up the early batches without wearing gloves. If you should meet Oliver, do not make jokes about his height.

Loneliness

There’s no aphrodisiac quite like Loneliness, especially if you live in Sydney and you’re lonely for someone who’s in Melbourne. (I suppose the reverse is also true.)

Oh sure, there are all sorts of other things that complicate it, like truth, beauty, pictures of the one you’re missing, boredom, and so on, and so on, but at the end of the day (or more accurately, the night) it’s just Loneliness, making the heart grow fonder and the groin go yonder.

Lot Six

Lot Six was the sixth in a series of mild hallucinogen that it was hoped would induce extrasensory perception in its users. Glorying in the scientific name of di-lysergic triune acid, it was nicknamed “booster acid” by the team that developed it at the behest of the Shop, a shadowy covert agency of the US government about which little is known.

A dozen subjects participated in the tests of Lot Six in 1969. Most of them died or went insane, but two of them, Andrew McGee (who developed minor coercive telepathic abilities) and Victoria Tomlinson (who developed an even smaller telekinetic talent) escaped from the Shop and spent many years on the run from it. After their marriage and the birth of their daughter Charlie, they discovered that a side effect of Lot Six was chromosomal mutation. Charlie developed a major pyrokinetic talent, which she used to destroy a Shop installation. Later, she brought the story of Lot Six to Rolling Stone Magazine, who created a minor scandal when the published it in 1980 (which was unfortunately quickly pushed from the front pages by the hostage situation at the US embassy in Tehran and the Presidential campaign).

Lotus

Growing on, and forming almost the entire diet of the inhabitants of an un-named island in the Mediterranean off the coast of North Africa, the Lotus plant is infamous for its powerful stupefying effects.

The people who live on this island have no recognizable culture other than consumption of the Lotus plant, extreme lassitude and a certain lazy friendliness to outsiders. The only known name for them is that given them in contempt by Ulysses, Lotus-Eaters.

Basically, the Lotus-Eaters live an idyllic life of being perpetually stoned. No wonder they so offended a man of action like Ulysses.

Love

Aside from cocaine, Love is the drug that the Seventies ran on.

At least, that’s how the legend runs. (And hey, the legend gave us Rumours, so clearly there’s something to it.) In practice, it was a lot more like Lust, or perhaps Sex Addiction.

Unlike the majority of other drugs I’ve listed here, Love has the advantage of being street legal – although like most drugs, you should still exercise some caution in when, where and with whom you choose to indulge 😉

Love Bomb

A weaponised aphrodisiac designed largely for urban pacification by the US military, Love Bomb never quite lived up to its promise. Based largely on existing MDMA drugs, it was supposed to be the ultimate in disarming the enemy: literally leading them to throw down their arms – and their clothes, and whatever remaining inhibitions they might have.

Never successfully developed, Love Bomb is rumoured to have turned up on the streets from time to time, although it is unclear whether it did, or whether the stories of it are simply urban myths (or exaggerated claims by dealers).

Related drugs: Urizen

Love Potion No. 9

Love Potion No. 9 is an aphrodisiac of undeniable potency, and great caution is urged in its use. It is a deep black in colour and smells not unlike turpentine.

As far as can be told, it is sold only by Madame Rue, a gypsy reader of palms and maker of potions who, as of 1959, lived at a place on the corner of Vine St and 34th St (now Jefferson Boulevard) in Los Angeles, California.

It induces feelings of extreme amorousness in those who imbibe it – so great that they may feel amorous towards inanimate objects, even – although how long these feelings last, the appropriate dosage, the best-before date, and the true identity of Madame Rue (as the name is most certainly a pseudonym) are details lost in the mists of time. Lost with them, apparently, are Love Potions Number 1 through 8, whose existence can be inferred from this Potion’s number, and possibly additional Love Potions numbered 10 or higher.

Luhix

Made from a plant that grows only in the outer plane known as the Abyss, Luhix is extremely painful to take – it is most often added directly to the blood stream via a self-inflicted wound, which is then bound up to prevent the drug from leaking out, and its immediate effect is agonizing.

However, for those users able to persevere through this pain, Luhix grants enhancements to physical and mental abilities for an hour or two, as well as an immunity to almost all kinds of pain. The one exception to this is the pain caused by Luhix itself – taking a second dose while the first is in effect, or indeed, for up to a day later, is even more painful, sometimes even to a fatal degree.

Related Drugs: Agony, Baccaran, Devilweed, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Mañanacillin

Technically, that should be MañanacillinTM, which is how it inevitably appears when mentioned in the pages of American Flagg!.

MañanacillinTM is of that class of substances euphemistically referred to as ‘morning after pills’ or abortifacients. Sold in pill form by the Plex, its existence serves primarily to reinforce the general disregard for the consequences of their actions that characterises most of the citizenry of 2030’s Chicago.

Curiously absent from American Flagg! is any religious group decrying MañanacillinTM as the offence against God’s will they would no doubt see it as.

Related drugs: Somnambutol.

Mandrake Restorative Draught

Mandrake Restorative Draught is cure for various magical curses and transfigurations.

One of its best known uses is to cure the victims of basilisk attacks, a use to which it was put to cure the several victims of such attacks at Hogwarts across 2002 and 2003. Mandrake Restorative Draught is unusual in that it equally efficacious when administered to ghosts as to the living.

Related Drugs: Deflating Draught, Hair Raising Potion, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.r of Secrets (First mentioned)

MDA-Cubed

Perhaps the ultimate aphrrodisiac, MDA-Cubed is a spectacularly potent date-rape drug that heightens the sexual impulse to the level of insanity. Users have been known to couple with anyone and anything, their usual sexual preferences notwithstanding. This is not limited to people, but also includes animals, plants and the occasional mechinical device or piece of furniture.

Immensely dangerous to social mores, MDA-Cubed is also in that class of drugs that is never as good afte the first time – not that this stops chronic users from chasing that high again and again.

Related Drugs: Blue Shock, Communion, Nightmare, Relapse, Slo-Mo, Wings and Zorro.

Mechanics

A rare cyberdrug that affects both machines and people, Mechanics is a hard drug to quantify. It is slow to build into an addiction, but irreversible in its effects long before that point.

Mechanics can only be taken by a human and an artificial intelligence in tandem – it is a source code level drug that rewrites the source code of those who take it. For a human, that means DNA.

Each use of the drug transforms a little more of the user’s body into inorganic matter, slowly transforming them into a cyborg at first, and later, an artificial intelligence altogether. The high from taking the drug might fade away, but the mutations never do.

Related Drugs: Jumpstart, Space and Tripwire 7.0.

Mega Dope

Little is known about Mega Dope other than that, on the mean streets of 2006 Detroit, it gets you Mega High! The Kickpuncher, a cybernetic cop whose punches have the force of kicks, fights a lonely struggle to end its scourge.

At least, he does in the fictional Kickpuncher movie franchise beloved of Troy Barnes and Abed Nadir, as well as several other students of Greendale Community College.

Related drugs: Joyvetrex and Relaxorex.

Mei Kuan

Mei Kuan is an extremely potent mind-expanding drug – a few drops of it could cause permanent insanity or death to all but the strongest-willed users.

It is of Oriental origin, and appears to be a preparation of a variety of drugs and herbs, very likely including opium. Under its effects, users experience heightened perceptions and cognition, transporting themselves into realms of abstract concepts and higher spiritual planes.

Related Drugs: beng lie

Miccrano

Miccrano is a traditional remedy for stomach upsets and digestive problems among the Filiaelian race.

It is minimally effective against poisons, especially heavy metal poisoning.

Related drugs: Castran’s Binder, Modhra Coral, Printimpolivre-bioxene, QuixHeal and Saarix-5.

Miruvóre

The exact translation of Miruvor or Miruvóre, is not known, but “death-defeater” is a probable etymological meaning. It’s certainly an accurate description.

Appearing in The Fellowship of the Rings, miruvor is a warm and fragrant clear cordial made by and consumed by the Elves. They do not reveal how miruvor was made, but it is thought to come from the honey of the undying flowers in the gardens of Yavanna in Valinor. It’s possible that this drink holds the secret of Elven immortality, although if so, it has no such effect on humans, hobbits or dwarves.

The cordial gives the drinker renewed strength and vitality, and is used by the Elves at their festivals. Some party animals, those Elves, huh?

Related drugs: Athelas, Ent-Draughts and Pipe-Weed.

Modhra Coral

Less a drug than a strong parallel to drugs, Modhra Coral is dispersed consciousness that lives in coral polyps local to the moon Modhra II in the Sisstarko system. It is a sentient hive mind, although the limitations of distance mean that its colonies can lose contact with each other, and although the guiding consciousness remains the same, information known to an isolated colony may be lost if that colony is destroyed.

Modhra Coral is a highly controlled substance on most worlds, as any cuts on the skin allow it to implant polyps in those have touched it and eventually control them. It has limited psychic abilities whose strength is dependent on the size of the colony, which it uses to communicate amonst itself, and also to impel still more people to touch the coral and fall under its control.

The consciousness of Modhra Coral is usually referred to as just “the Modhra”. It was a creation of the imperialistic and warlike Shonkla-raa race (now fortunately extinct) that survived its masters and sought to continue their misson.

As of the Earth Year 2085, it is believed to have been destroyed; although independent infectees (“walkers”) still remain at large, their numbers are believed to be insufficient to pose a threat.

Related drugs: Castran’s Binder, Miccrano, Printimpolivre-bioxene, QuixHeal and Saarix-5.

Mongoose Blood

Derived from the bodily fluids of one of the fastest of all mammals, Moongoose Blood is a superhuman level stimulant, capable of accelerating the bodies of users into speeds just short of light speed, visible to the naked eye only as lightning-like flashes.

Also known as ‘Goose Juice, the drug is highly illegal and the police force of Neopolis finds it a perennial problem.

An entire sub-culture has grown up around the use of Mongoose Blood, which can be best characterised as ‘extreme rave culture’. Goose music is so fast that to those not currently on the drug hear it only as a painfully high-pitched whine.

Related drugs: Amazo Pills, Darkshots, Hyperdrene and Xenite.

Mordayn Vapor

Mordayn Vapor, also known as Dreammist is an extremely potent hallucinogen, granting visions of such transcendence that many users find them so much more appealing than mundane life that it is one of the most addictive drugs in existence.

It is called Mordayn Vapor due to the way it is usually taken – by preparing the brown powdered herb that is the actual drug as a tea and inhaling the fumes that arise from it. Both the powder and its tea are deadly poisons, and experienced users know to dispose of them quickly and carefully, not least to reduce the chance of overdosing in an intoxicated stupor. The drug depresses both the wits and the constitution of the user while its effects last.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mushroom Powder, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Mugwump Jism

Secreted by the mysterious Mugwumps of Interzone, Mugwump Jism is a colorless liquid that produces intoxicating effects on humans.

In fact, Mugwump Jism actually comes in two finely distinguished varieties, with similar effects. Strangely, what excites the Mugwumps (who are sentient bipeds of about the same size as humans, and appear to be some form of amphibian) to produce this drug is artistic creation, especially of a literary variety.

However, they do produce it even without this inspiration, albeit at a slower rate, and it is a sad but not uncommon sight in Interzone to see a chained Mugwump surrounded by a small circle of addicts sucking upon its excretions.

Related drugs: The Black Meat, Bug Powder and The Drug That Does Not Exist.

Murtlap Essence

Murtlap Essence is created from the strained and pickled tentacles of Murtlaps. It is both a curative and anesthetic, soothing the pain of cuts and abrasions, and helping them to heal.

It is also effective in the treatment of certain other minor ailments of the skin, such as boils.

Related Drugs: Babbling Beverage, Doxycide, Dr. Ubbly’s Oblivious Unction & Garrotting Gas.

Mushroom Powder

Mushroom Powder derives from a rare blue mushroom, and is inhaled to produce hallucinations.

Its use is popular, especially with arcane spell casters, who prize the insights that it brings them, albeit at the cost of physical abilities being suppressed during its effects. Like many drugs, it causes great pain if over-used, although it takes three doses within a single 24 hour period to suffer this effect.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Redflower Leaves, Sannish, Terran Brandy and Vodare.

Mutant Growth Hormone

Originally a powerful, non-addictive mutagen devised by X-Man Hank McCoy (a.k.a. The Beast), Mutant Growth Hormone has since been debased into a less potent but more addictive form, and shown up on the streets of New York City, usually abbreviated to MGH.

MGH is created from the DNA of a mutant (or mutate), and grants the user with limited superpowers for a brief period. Although most sellers of the drug claim that the powers granted are related to the person who the MGH was harvested from, this is in fact untrue, and the powers granted arise from the activation of latent mutant genes in the user.

Known DNA sources for MGH include Hank McCoy (who made the original formulation from his own DNA and took it himself, which may account for both the potency and permanency of the effects), Leland Owlsley (the criminal known as The Owl) and Mattie Franklin (the third Spider-Woman). No verified sample has ever been created from the DNA of Peter Parker (Spider-Man) although dealers frequently claim him as a source of the drug.

Muzon

In the year 2035, Muzon is one of the most popular commercially available anti-anxiety drugs, the successor of Zoloft and Prozac. Little is known about it, other than that it is reasonably safe and has relatively few side effects.

NEURO

NEURO is an intelligence-enhancing drug, but is unclear exactly how it works – it may be a mutagen, a stimulant or a psychiatric, or some combination of these or other elements.

Questions of mechanism aside, the drug is known to be very effective.

NEURO is known to exist in most of a cluster of closely-related alternate timelines or eigenstates.

Related drugs: Ex-Tend, FEMFREE, FOREVER and ORGASMOR.

Neuro-Tryptalin

Neuro-Tryptalin is a drug developed to treat sufferers of Partially Deceased Syndrome (PDS) – zombies, in less politically correct words. It assists zombies – I’m sorry, PDF sufferers – in restoring normal brain function, and thus, returning to normal life. It is administered via injection, directly to the spinal cord.

The full range of the drug’s effects are not known, but they do suppress the zombie hunger. They also cause vivid flashbacks to the last attack committed when in zombie state, although these are believed to fade with time. Unfortunately, Neuro-Tryptalin is not effective in every case, and there is little other help to be had for them. (Let’s be honest, they’re put down like rabid dogs.) There are

Niathol

One of the more effective Truth Sera, Niathol is usually administered by syringe in quite small quantities – rarely more than 2cc’s, except for the largest people.

This is because it doesn’t take much more of it to kill. Niathol is stored frozen, but cannot be refrozen safely, and thus any remaining unused quantities of it must be disposed of carefully – molecular dispersal is usually considered the minimum degree of care.

Related Drugs: Alphanella seeds.

Nightmare

Deadly and dangerous, Nightmare is a drug that, as the name suggests, causes nightmares in the user. Perhaps more disturbingly, it implants pre-recorded nightmares in them.

Found only in Al Amarja, Nightmare is made from the excretions of tulpas – dream entities that have managed to acheive a physical existence in the mundane world. Pushers of the drug, known as Sandmen, gather this dung, and record the nightmares of potent dreamers by smearing it on their foreheads while they sleep.

The dung is then collected, and processed into an injectable serum, and sold to the rich and jaded whose capacity to experience strong emotions has atrophied.

Related Drugs: Blue Shock, Communion, MDA-Cubed, Relapse, Slo-Mo, Wings and Zorro.

Nitrolabe

Derived from the copper-based nine-fish of Centralia IV, Nitrolabe has several peculiarities compated to most drugs. The nine-fish secrete Nitrolabe as a poison that they use their spines to inject their attackers with. However, the poison only works on creatures who blood is copper-based. On creatures with iron-based blood, its effects are quite different.

Nitrolabe acts as a neural enhancer, increasing the speed and intensity of neural connections in the user to the extent that they are reduced to a twitching, orgasmic trance for the hour or so that a standard dose lasts. However, repeated usage causes neural connections to misfire or fail, causing pain, neural degredation and dystrophy, so that the user will over time come to require the drug in order to be able to function normally.

Related Drugs: Bentlam, Fayalin, Hadive, Ladolian, Thionite, Vee-Two Gas and VXN Gas.

NoLag

NoLag is an over-the-counter medicine for preventing jetlag. Unfortunately, it is not available until around 2034 CE. It is very effective, but a little hit or miss in its effects.

NoLag consists of two timed effects. The first is a sedative, to allow sleep, following by a stimulant to wake up the user. It is released on a time delay many hours after the sedative. NoLag is undeniably effective, but has been known to cause hallucinatory effects in the particularly sleep-deprived.

Nuke

Proclaimed by the Surgeon-General of the United States to be the most addictive and dangerous narcotic in human history, Nuke is apparently a mixture of several other drugs, notably benzedrine and scopalimine.

Available in a wide variety of flavours, each one a different colour, there is a Nuke for every mood – white noise, black thunder, red ramrod and blue velvet are listed, although red ramrod is far and away the most popular. All are distributed in ampoules about an inch and half long, which are injected directly into the user’s skin.

Made in Detroit by the psychotic drug lord and cult leader Cain, Nuke is no longer produced after Robocop killed Cain and destroyed his manufacturing facilities.

Nullergin-200

A hayfever and general allergy medicine, Nullergin-200 is effective not only against all known allergens, but also against the symptoms of the common cold. It also has a side effect of giving the user a feeling of emotional warmth and friendliness – a side effect that tends to lead to a certain sloppiness in one’s work ethic and apathy about the result, since one would rather socialise than work, and anyway, working too hard or too well would be mean to one’s competitors, who are basically nice people, right?

Nullergin-200 has since had its formulation modified, with the outer coating of the pills now a cumulative drug that increases the speed at which the anti-allergic is eliminated from the user’s body, returning the emotions of humanity to something more like normality.

Related Drugs: Cerebrocreatine, De-Tox and Super-Aktion

The Nuncio

Possibly the most powerful mutagen ever created, the Nuncio (Latin for ‘messenger’) was created by Dr Richard Fletcher in the late Sixties, in a private lab funded by Randolph Jaffe in Baja California, on the coast of the Pacific.

There are two versions of the drug, the lesser being a prototype that was tested on an ape named Raul and evolved him to more human state, making him sentient and capable of human speech. The completed Nuncio was a bluish serum that was known to move under its own power in search of a host.

The effects of the serum varied from person to person, but were always strongly reflective of the mental states of those who took it. Inevitably, it would grant them a degree of mystical power, including the ability to see and travel beyond our mundane reality to more fundamental ones. Three doses were made, and a total of five people are known to have taken the Nuncio: Fletcher and Jaffe, who each took a full dose, while the remaining dose was shared between Jaffe’s son Tommy, a woman named Tesla Bombeck and the ape-man Raul.

NZT-48

NZT-48 is a cognitive enhancer that activates “the other 90%” of the human brain. It increases recall, perception, problem solving ability, concentration and speed of cognition. As side effects of these, it massively improves self-confidence, focus and motivation. Oh, and it kicks in within 30 seconds of ingesting a pill.

It does have a number of notable side effects, however. For a start, hyping up one’s motivation sounds good, but NZT-48 pushes it to a point where inactivity is impossible. Decreasing one’s inhibitions sounds good, except that it includes moral inhibitions. When under the effects of the drug, one feels invincible, and entirely free from consequences.

One is, alas, neither of these things.

It is also massively physically and psychologically addicting. Withdrawal from NZT-48 is accompanied by visual distortions, blackouts, nausea and profuse sweating.

And finally, NZT-48 is illegal, and people will kill to get their hands on it.

Happy using.

ORGASMOR

ORGASMOR is a legal drug which is applied as a lotion. It is reputed to have aphrodisiac and lubricious properties, although these statements are made nowhere in the advertising.

In fact, its chemical properties are not terribly dissimilar to those of Coca Cola, and all the reported results can safely be attributed to the placebo effect.

ORGASMOR is known to exist in most of a cluster of closely-related alternate timelines or eigenstates.

Related drugs: Ex-Tend, FEMFREE, FOREVER and NEURO.

Orpheus

Orpheus is a vampire drug, a mystical opiate which is taken in with the blood of those they feed from – the humans typically inject the drug into their bloodstreams before the feeding.

The enchanted drug can be easily tasted on the blood, and its effects on the vampire are very quick, especially if the dose is large. Of course, a dose that large will tend to knock out the human, leaving them in a comatose – and potentially fatal – state.

Smaller doses can be euphoric for both parties, but larger ones induce what can only be described as a vision quest, in which both parties travel through the history of the vampire in question, and choices made along the way determine whether either of them ever wakes up again. This experience of taking the drug has been described as being taken to Hell and left there.

Related Drugs: Black Frost, Calendula, Calynthia Powder and Gill Man DNA.

Ortho Orange #42

A mysterious and deadly substance, Ortho Orange #42 has been illegally dumped by an un-named American corporation in at least one vacant lot, possibly in Philadelphia. Little is known of its chemical composition or intended use, but its effects on both human and canine subjects are well-documented.

One human subject, “Scotty”, developed a blood-clotting disorder as a result of his exposure, in addition to his skin turning green, losing his sight, and requiring nasal tubes to breathe. At this point, barring a miracle, his prognosis is terminal. A canine subject experienced less dramatic effects, although his once grey fur was changed to a yellow shade by exposure to the same substance.

Pahzik Horn

The Pahzik are a species of semi-domesticated herd animal, native to the planet Kupoh a long time ago in a galaxy far, far away. Their meat is tasty and nutritious, but it is their horns that they are most prized for.

Pahzik horn is reputed to have aphrodisiac powers, and a thriving black market exists in selling it to various off-worlders, usually ground into a powder for easier transportation and consumption. It is unclear what, if any, powers Pahzik horn possesses beyond the power to separate rich idiots from their credits.

Pain

Made in the depths of Hell from the sufferings of the damned, Pain is a gray powder. It is treated much like snuff by the demons who take it, and usually stored in snuff boxes.

The effects it has on the demonic physiology are as many and as varied as those physiologies, although the two universal constants are that it enhances the pleasure of sex, and that, although it is possible to resist the drug’s effects, it is painful to do so.

When used by the damned themselves, it appears to intensify sensation to a painful degree.

Painaway

Painaway is a bog-standard pain killer which treats such ailments as headaches and menstrual cramps. It is produced by Bosh, and advertised on the crappier sort of home video tapes in the Thatcher-era United Kingdom.

Painaway is unique in advertising history for claiming to soothe the pain of Hell’s torments. The veracity of this claim remains unsubstantiated.

Pattern Perception

Pattern Perception is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

Pattern Perception is a drug that immensely hikes up the user’s spatial perception. Although there are minor visual distortions – mostly contrail-like effects trailing after moving objects – for the most part, it makes it easier to perceive and move through three dimensional space. It’s particularly good for playing fast moving sports or games like pool.

Related Drugs: Apprehension of Beauty, Buzz, California Mello, Funnybone, Get Wired, Rhinoceros & Verbality

Pax

The Pax, or to give it its full name, G-23 Paxilon Hydrochlorate, was a sedative used in a social engineering project that failed disastrously. The Union of Allied Planets released it into the atmosphere of a newly settled world named Miranda in the year 2506.

In very short order, the Pax pacified the vast majority of the population there into complete inactivity. They simply stopped, wherever they were and whatever they were doing, and waited, inactive, until they died (presumably from starvation and dehydration, in most cases).

They were the lucky ones.

One tenth of one percent of the population found that the drug instead boosted their aggression to a level described as ‘beyond madness’. They became brutal, sadistic and cannibalistic, given to acts of rape, torture and self-mutilation, and were known as Reavers. The truth of their origin was revealed to the galaxy at large by Malcolm Reynolds and his crew in 2518.

Penzerol

Penzerol is a strong and mostly effective truth serum when used on humans. Only those with unusually strong wills – or alien DNA – can resist its effects.

Of course, it does have a nasty side effect of potentially causing permanent brain damage, and as with most drugs, too great a dose is fatal.

Unusually, it is part of a suite of other drugs intended to be used together, notably sedatives which help prevent the heightened physical responses that interrogation so often entails from getting in the way of actually obtaining information.

Related Drugs: Red Skeezix

Pepperup Potion

Pepperup Potion is a magical cure for the common cold, and reasonably effective at doing so.

It does, however, come with the side-effect that steam is emitted from the ears of those who take it for several hours after taking it. If muggles ever discovered it, it would be enormously popular among the mainstream for its curative effects, and among steampunks for its side effects.

It was first created by Glover Hipworth, although it is unclear whether he did so in the late 18th or early 18th centuries.

Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Polyjuice Potion, Skele-Gro & Swelling Solution.

Pipe-Weed

Originating in Numenor, from whence it was brought to Middle Earth by the Numeroeans, Pipe-Weed is an analogue of tobacco. The flowering plant that it grows from is called Galenas, and was prized by the Numenoreans for the sweet scent of its flowers.

It was first cultivated and smoked by Hobbits, specifically one Tobold Hornblower from the Southfarthing of the Shire, and the best Pipe-Weed is still considered to come from that region.

From the Hobbits, the use of it for smoking spread among Men and Dwarves, and even Wizards, radiating out in particular from the crossroads of Bree, where traders from all those peoples regularly congregated. As such, other common names for Pipe-Weed include Westmansweed and Halfling’s Leaf.

Related drugs: Athelas, Ent-Draughts and Miruvóre.

Pitrolux

Pitrolux is the trade name under which the chemical testopheromenal is sold in 19 countries including the USA. An underarm deodorant lotion and ‘bedroom enhancer’ for men, Pitrolux is a purple gel (sold with its own, allegedly patented, ‘soft-glide applicator’), also notable for being scented with juniper- (later replaced by ‘country apple’)…

…and for the fact that its overly testosterone-rich formulation causes numerous unpleasant side effects, such as excessive hair growth (especially on the face and torso), elongation of the larynx, enlargement of the testicles, random tissue deformities (especially on the areas of skin where Pitrolux is applied), painful and potentially life-threatening erections, truly volcanic acne, and a tendency for heavy users to become so strongly juniper-scented that no other scent can be detected from them.

It is the subject of a class action suit on behalf of numerous displeased former customers (including, notably, an all-female cheerleading squad from Texas), and the manufacturer is expected to settle out of court.

Plomox

One of the best anti-arrhythmia drugs on the market, Plomox is priced accordingly – that is, ludicrously high – by its manufacturer.

For that reason, and because it can have deleterious side effects, such as causing hypertension when administered to diabetics, most doctors have a love-hate relationship with the drug. They love how effective it is, but they hate that its prohibitively high cost places it out of reach for many patients who might otherwise benefit from it. The company that created Plomox is facing a lawsuit over the drug, but few details of the case’s specifics are known.

Related Drugs: Cloveritol.

Polyjuice Potion

Polyjuice Potion is an alchemical preparation that allows a human drinker to temporarily assume the form of another person – although only a particular person. In particular, it cannot be used to take the form of any non-human – although numerous attempts have ended in the potion drinker being stuck in some sort of in-between form.

The potion is a difficult and time-consuming one to prepare – among other things, it needs to brew for a month after its final brewing – and one of the most difficult to acquire ingredients is a sample of the target person, usually hair, although other substances will work just as well. Polyjuice Potion is also highly variable in the duration of its effect, with the quality of the numerous ingredients and the skill of the brewing both influencing the outcomes.

Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Skele-Gro & Swelling Solution.

Poudre de la Mort Vraie

Both a drug and a poison, Poudre de la Mort VraieThe Powder of True Death or Powder of the True Death, depending on your translator – is specifically designed for use by vampires. Created by Signalman Reynolds, formely of His Majesty’s British Army, it is extremely potent and addictive to vampires.

Reynolds, whose own wife had been a vampire, spent decades discovering how to create a substance that vampires would be attracted to. The actual formula for the creation of the grey powder is unknown, although it includes the dust of ground up mummies and assorted alchemical treatments.

Its effect on vampires is exactly what Reynolds intended: it has a euphoric rush, but leaves the vampire overwhlemed with the guilt of all their actions (both as a human and as a vampire) and not at all hungry for blood. The idea is that the vampire will be tortured by both remorse and starvation as they slowly wither away to nothing – the taste of blood will lead a vampire who has consumed Poudre de la Mort Vraie retch and vomit.

A large enough dose of the untainted blood of another vampire will throw off the effects of the drug, and a small enough dose can be outlasted – after a few days, normal vampiric instincts will reassert themselves.

Priapism Formula

Developed by a Dr. Duran of Hopkins University and her faithful assistant, Calvin, the Priapism Formula is a highly effective aphrodisiac – as the Dr and Calvin discovered when she accidentally inhaled the fumes from it one day.

From there, the Priapism Formula next turned up as the secret ingredient in the sauce used on burgers at Pop’s – a start-up operated, not coincidentally, by friends of Calvin’s who had stolen the formula from Duran’s lab. Somewhat more dilute in its effects when consumed with a burger, fries and a milkshake, the Priapism Formula – now called the Secret Sauce – remained a mild aphrodisiac and something of a euphoric. Unsurprisingly, this made Pop’s quite popular.

Printimpolivre-bioxene

Printimpolivre-bioxene is both an hallucinogen and a paranoic. A reasonably well known compound to medical science (at least, in 2085), it is particularly effective against the alien Shorshian race.

It is often used as a poison. People who have been dosed with it can sometimes be detected by the sickly sweet odour it emits in their perspiration, by medical analysis of their bloodstream, and of course, because they’ve suddenly started seeing things that aren’t there and not trusting anyone.

Related drugs: Castran’s Binder, Miccrano, Modhra Coral, QuixHeal and Saarix-5.

Prisoner’s Honey

Made solely by the bees who gather pollen from the subterranean black roses of Fallen London, Prisoner’s Honey is an unusual drug which transports those who use it physically into the realm of dreams.

The realm of dreams, it should be noted, is even more bizarre and alarming than Fallen London, which is no low bar to clear. Still, there are those who choose to visit it, and Prisoner’s Honey is the method they most often choose. Just sleeping in for amateurs.

Canny readers will have noticed that nowhere is how the users return from the Realm of Dreams specified.

PRO-Vyril

PRO-Vyril is an erectile dysfunction treatment produced by the somewhat shady pharmaceutical conglomerate Calenture-Deutz. Like Cialis or Viagra, it is produced in pill form; unlike them, it is not nearly as pronounced in its effects.

However, it turns out that the market has a niche for a kindler, gentler produced of erections in older men, and PRO-Vyril has been a solid if unspectacular earner for Calenture-Deutz.

Related Drugs: Bynogol and Zembla-4

Profillica

A hair growth drug that was later banned by the FDA, Profillica actually did have some positive effects of hair growth, albeit not always on the top of the head.

It was banned as a result of its negative effects on the central nervous system (it frequently causes uncontrollable spasming). Profillica is widely believed to be made from monkey hormones, but the truth of this assertion is unknown.

Related Drugs: Euphorazine, Teamocil & Zanotab.

Provasic

Provasic is a drug produced by Devlin MacGregor Pharmaceuticals which was announced as a non-invasive treatment for arterial plaque, one that would reduce the risks of heart attack and other heart problems. IN early tests, it was referred to as RDU-90.

Sadly, it was not as advertised. It caused severe liver damage in a small but significant number of patients it was administered to. The company was aware of this, and conspired to frame a Dr Richard Kimble for falsifying the tissue samples enabling FDA approval.

This scheme ultimately backfired, and Kimble exposed the conspirators with a little assistance from US Marshal Sam Gerard and his team. As a result, Provasic never went to market and several employees of Devlin MacGregor faced criminal charges for their roles in the conspiracy.

Prozium

Prozium, acclaimed as the great nepenthe, the opiate of the masses and the glue of the great (read: repressively dystopian) society, is a highly potent sedative that deadens nearly all emotions to a dull hum.

Prozium is described as an anesthetic for the emotions, which implies that they’re still there, they just can’t be felt. Although given that it is apparently still necessary to destroy any art that might provoke an emotional response, one might well ask just how effective it truly is.

Still, there are some people who regard the sacrifice of all the higher emotions as a fair exchange for getting rid of the lower ones – and they’re the same people who run the world.

Psi-blockers

A perfectly legal drug developed by the Psi-Corps in order to suppress the telepathy of those psis who do not wish to join the Psi-Corps.

Psi-blockers take about three hours to take effect after they are administered (via direct injection), although the dosage size seems to affect how long they last for – a standard dose for a registered telepath lasts for a week. Unfortunately, doses that large have the unfortunate side effect of causing depression in long term users (although sociopaths seem immune from this effect).

Related drugs: Dust.

PX-41

PX-41 is a potent mutagen created by the supervillain El Macho. It turns anyone injected with it into an giant white-haired purple rage monster, whether they’re an articially created life form or a dangerous Mexican supervillain.

Both PX-41 and its antidote were created by Dr. Nefario, an elderly British mad scientist in the employ of El Macho (although he betrayed him to create the antidote). All known samples are nor presumably in the custody of the Anti-Villain League, although Dr. Nefario could no doubt whip up more easily enough.

QuixHeal

An analgesic and healing promoter, QuixHeal is a trade name of a human-specific healing agent that assists the body in repairing the damage done by physical injuries.

QuixHeal can be combined with other painkillers and even consumed with alcohol with no ill-effects. At higher doses, it tends to cause drowsiness and deep sleep, but it continues to work on repairing the body even while the user is sound asleep.

The effects of Quixheal are limited, and it is not a substitute for major surgery. However, it will fix most bruises, scrateches, grazes, sprains and the like, up to hairline bone fractures. Anything more serious will require proper medical attention.

Related drugs: Castran’s Binder, Miccrano, Modhra Coral, Printimpolivre-bioxene and Saarix-5.

Rapture

A bright yellow powder ingested directly, Rapture is taken as a party drug, but has the unusual effect of increasing the cognitive power of its users, especially with regard to mathematical calculations. Even a single dose seems to have this effect.

It also creates limited psychic powers, including the ability to psychically attack others, and also creates a limited mindlink between users – a mindlink that can be used to increase the power of the psychic attacks. The mindlink allows access to memories and also the ability for the most heavy users to control the less heavy, effectively over-writing their minds and using them to increase the power of their own mental powers.

It is also powerfully addictive – a single hit is enough to get a user hooked. It was created by a sentient AI, with the intention of controlling humans. Fortunately, it had but one source, a young chemist in Texas who committed suicide while under the effects of the drug. It appears that the effects are temporary, and wear off when the drug is no longer consumed.

Rat Tonic

Rat tonic is a healing potion for specifically intended to heal rats. It can also be used to treat the symptoms of ageing in rats. It is sold in a small red bottle at the Magical Menagerie in Diagon Alley, and presumably at similar locations elsewhere.

It is also the case that excessive use of Rat tonic can result in the rat drinking it becoming engorged, enlarged and even deformed. It is recommended that the directions on the bottle be followed to the letter.

Related drugs: Confusing Concoction, Shrinking Solution and Wolfsbane Potion.

RC-12

RC-12 is a potent sedative, usually used by law enforcement to sedate and apprehend violent criminals. However, it was once deployed far more widely, against an irrevocably hostile alien race, the La’heng (from the planet of the same name).

Unfortunately, the La’heng are a highly adaptable species who respond to their environment on a genetic level. Within a generation of the deployment of the RC-12, every member of the La’heng species was genetically altered into subservient beings who are psychologically – and physically – unable to function without a master (called a “shinai” by the La’heng).

Related Drugs: Carvati’s Cure, Kosh and Rejuvenex

Redflower Leaves

Redflower Leaves are the crushed leaves of a small big plant. It is prized for its ability to improve hand-to-eye coordination, to such an extent that witness reports tell of users not just seeming to move faster than usual but actually moving at superhuman, albeit low, speeds.

The effects of Redflower Leaves are not long lasting, and rarely last more than 10 minutes or so. It is near impossible to overdose on Redflower Leaves, as the effect of overuse is nausea, causing the drug to be expelled from the user’s body and quickly reducing its effects.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Sannish, Terran Brandy and Vodare.

Red Skeezix

Described as a “recreational mindbender”, Red Skeezix is most likely an hallucinogen, a stimulant or both.

Little is known of the drug other than its dubious legality, being popular primarily in the more lawless regions of the Perseus Spur worlds, and presumably, being not-un-enjoyable to take.

Related Drugs: Penzerol.

Regeneration Potion

A Regeneration Potion is used to heal and restore a wizard whose after extreme physical damage, up to and including maiming and disfigurement. It is a work of the darkest magic, requiring the flesh of an ally and the blood of an enemy among its ingredients.

The entire body of the wizard being treated must be immersed in the cauldron in which it is brewed, so only the largest of cauldrons can be used in its creation. For all of these reasons, it is very rarely prepared.

In 1994, this potion was brewed to resurrect Voldemort, using the blood of his enemy, Harry Potter. The use of Potter’s blood would prove an error, as due to other enchantments placed upon it, it prevented Voldemort from killing Potter – but not the reverse.

Related drugs: Sleekeazy’s Hair Potion.

Rejuvenex

Rejuvenex, as the name suggests, is a drug and hormone treatment specifically designed to fight off the ravages of aging. It does exactly what it promises to, restoring skin and muscle tone to the peak of young adulthood.

Rejuvenex isn’t cheap, but it’s often considered worth it – repeated applications can extend a normal human lifespan to the region of 200 years of life.

Related Drugs: Carvati’s Cure, Kosh and RC-12

Relapse

Relapse isn’t so much a drug as a way of making drug use less safe and predictable. It’s a chemical coating applied to almost any other drug that dissolves inside the user’s stomach at some random time after ingestion.

Long term users of Relapse sometimes claim that the drug has a malign sense of humour, and deliberately waits to mess people up by going off at the worst possible time. Possible side effects of use include heightened paranoia, a tendancy to anthropomorphize and denial.

Related Drugs: Blue Shock, Communion, MDA-Cubed, Nightmare, Slo-Mo, Wings and Zorro.

Relaxon

Relaxon is a tranquiliser.

It is sometimes used for years at a time, as its advertising claims that it is non-addicting – although it’s unclear how true that is, or what other side effects it might have.

Related Drugs: Ca-Fix

Relaxorex

Produced by Futurza – the same pharmaceutical company that brought the world both Fibromyalgia, and a highly-priced (not to mention dubiously effective) cure for Fibromyalgia – Relaxorex was a 2013 anti-depressant and that was heavily pushed onto the medical community.

Despite what stories in the media may have said, Relaxorex does not actually cause people to give up on their dreams. That’s just a side-effect.

Related drugs: Joyvetrex and Mega-Dope.

Returné

Although marketed as a drug, Returné is actually a nanotech-laced serum with the rather unusual effect of raising the dead – although not forever. A single injection lasts for about 24 hours before needing to be replenished (although actual death doesn’t result for another five or six days).

Because users of Returné are actually dead, they are immune to aging and illness. In fact, they are mnore or less immune to any thing that might cause death other than immolation, dismemberment or dissolution (that is, acid bath suicide).

The drug was produced by shadowy Big Pharma company Pharmadene, which goes a way towards explaining why this nanotech miracle isn’t permanent when it so easily could be – where’s the money in that? The drug has not yet been cleared by the FDA for public use, although it rapidly leaked out through an underground of criminal funeral homes, from which it was sold at exhorbitant prices. As a result, a shadowy war of corporate espionage and covert law enforcement broke out, whose outcome is still unclear at this time.

Rhinoceros

The pharmacometrics of the mid-twenty-first century are sufficiently advanced that the production of what has often been seen as more the domain of magic than science is now possible: Rhinoceros is the world’s first fully working aphrodisiac.

Why Rhinoceros? Because traditionally, it was believed that the horn of an actual Rhinoceros was an aphrodisiac – which is why these majestic beasts were hunted to extinction.

The drug Rhinoceros was a binary drug – taken in two parts that combine in the digestive system of the user.

Related Drugs: Apprehension of Beauty, Buzz, California Mello, Funnybone, Get Wired, Pattern Perception & Verbality

Saarix

A deadly poison, Saarix-5 is a nerve gas. It is quick acting, but also fairly quick to disperse, as it oxidises on exposure to the air. It is almost universally deadly to all species exposed to it, including humans, Bellidos, Cimmaheen, Juriani and Halkas.

Saarix-5 is also able to be stored as an inert solid, in which form it is fairly safe, and can safely be handled with bare skin. Such forms are often used to smuggle the gas through checkpoints, usually with some sort of quick detonation device attached to allow its use.

Related drugs: Castran’s Binder, Miccrano, Modhra Coral, QuixHeal and Printimpolivre-bioxene.

Sannish

Sannish is a bluish liquid made from a variety of ingredients ranging from wolves’ milk to the powdered form of a desert plant.

Sannish is a mild intoxicant that causes physical bliss and an immunity to pain for several hours. However, it also causes a stuporous languor in the user, who will be disinclined to take any physical actions, or even think particularly hard. It is a popular drug whose users can be easily spotted by the blue stains on their lips, which become permanent if usage goes on long enough.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Terran Brandy and Vodare.

Scolopendium

Scolopendium is a highly addictive plant extract native to the world known as The Fourlands. It is a potent hallucinogen, and strong enough doses will translate the mind of the user into another reality known as the Shift (which is apparently some form of dimensional nexus). Indeed, if the body of the user should die while the Scolopendium remains in effect, the mind of the user will live on in the Shift.

Scolopendium is illegal – although it does have some medical uses – and is known by several different street names, of which Cat is the most widely used.

Aside from its hallucinogenic effects, the physical effects of using this drug resemble those of heroin fairly closely, both in terms of the swoon it sends users into and also the effects of withdrawal.

Scramble

Scramble is a euphoric designed more or less accidentally by CIA-sponsored pharmacists in an attempt to create a better class of interrogation enhancer. Its intended effect was to intensify memory, but although that is indeed one of its effects, it does so in a way that is more or less useless for interrogation purposes.

Scramble brings back good memories accompanied by a euphoric high, which often makes its users appear very withdrawn and physically uncoordinated. But after a peak is reached, a downward cycle begins: the memories become progressively less pleasant and the euphoric effects slowly turn depressive.

Despite this, Scramble is at least as addictive as most opiates, and has similar physical effects with long term use. It is also quite potent: a single kilogram of Scramble will last even a heavy user for a year and then some.

Sentry Serum

An unlikely chemical capable of tapping into that same power that caused the Ten Plagues of Egypt – i.e. the Wrath of God – Sentry Serum was created by a un-named Professor in an attempt to recreate the Super Soldier Serum.

Clearly, he succeeded beyond his wildest dreams. Just as clearly, the addict and thief who took the sole, untested sample of the serum, Robert Reynolds, was manifestly unsuited for the nigh-infinite power it unleashed in him.

It is unclear whether the serum caused his multiple personalities, or merely exacerbated an existing tendency in Reynolds, but in either identity – the ‘heroic’ Sentry or the evil ‘Void’ – he had more power than he could easily control. With his death, it is unlikely that the serum will ever be recreated.

Shocktoxin

Shocktoxin was created by an unrevealed US military contractor for use by S.H.I.E.L.D., who in turn issued it to members of the Secret Avengers team. Crafted into flechettes with a monofilament edge, Shocktoxin projectiles could slice through almost any armour, and shots that missed left little evidence as the compound dissolved in minutes if left in the open air.

A hit from a Shocktoxin flechette would allow the nerve toxin to do its work – and a single flechette can knock out a healthy bull for about six hours. Human test subjects reported experiencing truly horrifying nightmares while knocked out by the drug. It is not known what the bull experienced.

Shrilanka

Shrilanka, active ingredient tshrillangaflogizini, is anti-depressive intended for use by teens and adults with moderate to severe bouts of depression, although also legally prescribable for children and pets.

Known side effects of Shrilanka include perineum incompatibility, swelling, pain, pineapple sized lesions, constipation, dry mouth, wet eyes, insomnia, drowsiness, blurred vision, and dizziness upon standing up too fast (which is to say, at anything more than about a quarter of normal human speed).

But, after 10-12 weeks of use, it will help to make the symptoms of depression and suicidal ideation go away, and make the user much less disturbing to their co-workers.

Shrinking Solution

Shrinking Solution is, as the name suggests, a potion that causes the drinker to shrink. It is primarily used to transport livestock.

However, the potion does not merely cause shrinking, but also causes the imbiber to become younger (which often also results in a loss of size, if the reversion continues into childhood). As a result, it must be used with great care.

Related drugs: Confusing Concoction, Rat Tonic and Wolfsbane Potion.

Skele-Gro

Skele-Gro is a well-known potion manufactured by Rubens Winikus and Company Inc. It is an aid to healing, which makes broken bones knit together more rapidly than they naturally would.

Unfortunately, it has several major drawbacks – it tastes terrible, it burns the throat on the way down, the bone-knitting process is still slow by magical standards while also creating excruciating pain, and it gives off smoke in a disconcerting fashion when its bottle is opened. For lack of a better replacement, it remains a go-to part of magical medicine treatments.

Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion & Swelling Solution.

Skullbustium

A drug whose very name suggests that it is not for the casual user, Skullbustium is the single most popular legal hallucinogen in America, likely because of its strength and appeal to machismo.

A very potent drug, Skullbustium appears to combine the effects of a large dose of LSD with those of amyl nitrate. As such, great care should be exercised in taking the drug, but of course, rarely is.

Related drugs: Skullbustium, Triptine, Truth and Consequences and Yaginol.

Skyfish Testes

How metafictional can a metafictional drug get? Skyfish Testes is a strong contender for the most metafictional drug ever. Not only is it explicitly fictional in its own context, but that context is an hallucination occurring as part of a larger story, rendering it doubly fictional.

Skyfish Testes, if they existed, would be a treatment for cancer of the soul and mental cirrhosis – although not one that Delmar Insurance would cover. But they don’t exist, and to claim that they do is just silly.

Everyone knows that skyfish don’t have testes…

Sleekeazy’s Hair Potion

Sleekeazy’s Hair Potion is a cosmetic treatment used to make messy hair more manageable.

While very effective, application is a bothersome and time-consuming process, meaning that it is used for special occasions rather than daily by most users. Also, for reasons unknown, but presumably magical, its use is not recommended by those with red hair.

Related drugs: Regeneration Potion.

Slo-Mo

A stimulant that slows perception of time, Slo-Mo is the drug of choice for those in Al Amarja who wish to either heighten their orgasms or improve their combat reflexes.

A single dose does not last long – thirty minutes at the outside – although for its two most common uses, that is generally more than enough. Slo-Mo was created by Dr Nussbaum on Al Amarja, but is now produced by organised crime networks and largely used by low level enforcers of those same networks.

Prolonged use tends to result in brain damage, and even first time users may suffer such effects. The heightened firing of the neurons induced by Slo-Mo can also result in users becoming catatonic.

Related Drugs: Blue Shock, Communion, MDA-Cubed, Nightmare, Relapse, Wings and Zorro.

Smilex

Perhaps more indicative of the insanity of the Joker than anything else about him, Smilex is a deadly poison that causes horrific facial deformations, usually in form of a rictus grin.

Smilex is made in both liquid and gaseous forms – the gas resembles a green smoke. The liquid can be mixed into almost any foodstuffs.

The puzzling thing about Smilex is the business plan behind its distribution. The Joker gives it away, seeking the widest possible range of people in Gotham, with the intent of killing them. Surely, this is insanity by any modern standard: the total absence of anything even resembling a profit motive – in fact, the Joker probably took a loss on the deal.

Snow Crash

Snow Crash exists in two forms, although it’s unclear how similar their effects are. The first form is as a blood serum taken from existing users, which induces a number of effects, the most apparent of which is glossolalia or speaking in tongues.

The second form is as a cyberdrug, which specifically disrupts the thought processes (and Metaverse avatars) of experienced coders. This drug takes the form of binary code that is somehow able to derange the thought processes of those who look directly at it, leaving them, so far as medical science can detect, like the victims of an induced stroke.

Both forms of the drug are connected to a sinister cult that is apparently seeking to take over the world. It’s always something.

Somnambutol

Technically, that should be SomnambutolTM, which is how it inevitably appears when mentioned – even when a character says it name in dialogue (I always wondered if they actually said the TM’s or not – Mr Chaykin, if you’re reading, please let us know :)).

A recreational barbituate and hallucinogen, SomnambutolTM, is sold in pill form by the Plex, and is soluble in most common drinks. It does not seem to have much of a taste when in drinks, so it’s presumably a popular date-rape drug in the Chicago of the 2030’s.

It is also available in a more concentrated aerosolised form, in which it is commonly used by law enforcement and private security agencies for crowd control, since it knocks people out for about an hour, and does so quickly and mostly harmlessly – although use does seem to lead to slight hangover-like symptoms afterwards.

Related drugs: Mañanacillan.

Soy Sauce

No, not that kind. Soy Sauce is a mysterious substance of curious and supernatural potency. Even a small dose will permently grant clairvoyant and other enhanced sensory abilities to the user. Of course, given the hallucinogenic and intoxicating effects of the drug, it can take the user a while to realise that these things are actually happening. And that’s just the start.

Possibly being a demonic entity in the form of a drug, or arising from an alternate timeline where bio-technology is considerably more developed. Certainly, among the abilities it seems to grant are time travel and dimensional travel. But its origin remains a mystery…

…for now.

Space

Space is a drug that replicates the experience of super-modernity. Which is to say, it creates the feeling of being endlessly between places in space, always between moments in time. It is a hallucination of the emotions one feels while trapped in an airport lounge waiting for a terrifyingly overdue flight, only with less interesting decor.

Why anyone finds this attractive is beyond me, but you know kids these days…

Related Drugs: Jumpstart, Mechanics and Tripwire 7.0.

Spanish Fly

One of the few placebos ever to be actually to be advertised as being a “Genuine 100% Placebo” – with reference made to the proven medical effect – the Spanish Fly placebo racket was the brainchild of con-man Jack McGreary.

Worrying about one’s sexual prowess is a Depression-proof market niche, something that allowed McGreary and his confederates to rake in a massive profit from selling sugar pills all over America in 1939. In fact, so successful was this racket – even at 1939 US $6.50 for a packet of pills – that the market proved to have room for two higher end placebos, Spurious Spanish Fly ($14 a packet) and Psuedo Spanish Fly ($25 a packet). Aphrodisiacs – even spurious ones – are always in high demand.

Like most good cons – and in a sense, this wasn’t even a con, so long as you were bright enough to look up placebo in the dictionary – it lasted until the con-men got bored with it.

Special H

With eight times the strength of ordinary Hormone Replacement Therapy estrogen patches, Special H a.k.a. Super HRT first became available in England through the machinations of a Calais-based drug-running syndicate.

Illegal to sell in England, it was distributed by a criminal syndicate based in Little Stempington, who smuggled 300,000 patches into the country in 2006. The street value of this import was estimated at 7,500,000 pounds.

The effects of Special H vary from user to user, but often include a heightened libido and uncontrollable mood swings.

Spike

Spike is a cheap stimulant that comes in the form of pills taken orally.

The Onion

Originally developed by the Pentagon as a drug for military personnel, the side-effects of the drug included sociopathic impulses that even the US military deemed excessive. Spike‘s other effects include a rush of physical strength and invulnerability to pain during its two hour window of effect.

After tests of Spike were discontinued by the Pentagon, it was adopted by the CIA as one of the “New Ghetto Drugs for ’98” collection.

Related drugs: Blue Glass, Brainscratch and Zom-B.

Splat

Splat is a deranging drug disguised as “a brown drink with bubbles”, and sold as a soft drink in the late 1990’s. Its resemblance – especially as concerns its look and taste – to a certain other “brown drink with bubbles” is presumably far from coincidental.

Created by the evil multi-millionaire Rolston Brocade, it was a modern version of a drink from Renaissance Florence, Splatso. Fortunately, Leonardo da Vinci devised an antidote to it, which was recreated by the Glam Metal Detectives. This was then marketed as Splodge, and later substituted for Splat on the production line, driving it off the market.

Even a small dose – not even a full can of soft drink – causes numerous side effects, the most visible of which are crossed eyes and a loss of physical coordination. Psychological effects include delusions of grandeur verging on megalomania, with the accompanying increased loudness, bossiness and arrogance.

Strim

An extremely potent mutagen, Strim is the drug of choice in Turn Neighbourhood, the hardest and weirdest place in the entire City. It wreaks havoc on the user’s DNA, deranges their perceptions into what can only be described as an alien state (no two alike, yet) and largely as a result of the foregoing, kills a hell of a lot its users.

Its only practical use is to transform one’s DNA so thoroughly that DNA-coded poisons and such will no longer recognize the user as their target – a highly specialised and largely criminal endeavour.

Related Drugs: Dilligenz, Dopaz and Jahavan coffee

Substance D

Also known as Slow Death, Death, or just plain D, Substance D is a powerful psychoactive drug derived from a small blue-flowering plant, Mors ontologica.

The drug dampens the links between the left and right hemispheres of the brain, causing the two hemispheres to function independently. As a side effect, the user experiences vivid hallucinations (which are a side effect of the two sundered hemispheres attempting to reconnect). As the nickname Slow Death suggests, it is lethally addictive; long-term use can lead to two separate, mutually unaware personalities.

Substance D is produced at farms run by an organisation called New Path. Here, the Mors ontologica flowers are grown, and refined into the drug. These farms are staffed primarily by addicts of the drug, sent to them for their rehabilitation.

Succinylcholine

A powerful sedative, effective against humans and most bala (magical sentients), Succinylcholine is the preferred drug of the Reason regime for use as an anesthetic and paralytic.

Its use is contraindicated on the deep space dwelling redworm species, whose acidic blood reacts with Succinylcholine rather differently, causing it to act as a powerful stimulant to the dangerous beast.

Super-Aktion

Devised by Banner Value Drug and Vitamin Laboratories, Inc. as an antidote to their all-too-successful product, Cerebrocreatine, and marketed as a liquid inhaled in suspension (much like asthma medicines), Super-Aktion stimulates the parts of the brain that control decision-making and impatience.

Super-Aktion is, unfortunately, a little too effective in its purpose, as one of the side effects of the hastier decision-making and impetus towards action it causes is a disregard for the potential dangers of the likely outcomes of the actions taken under its influence.

Related Drugs: Cerebrocreatine, De-Tox and Nullergin-200.

Super-Quinine

In the future of 3001, after the collapse of civilisation as we know it, when the world has changed not quite beyond recognition, malarial fevers resistant to ordinary quinine will kill thousands.

But in some parts of the world – the mountains near the lake that now covers Portland, Oregon, for example – a cure may be found. That cure is Super Quinine which is found in the leaves of the plentiful rhodeodendrons that grow in that area.

It is generally accepted that these particular rhododendrons, although found growing wild (and only later cultivated) are not naturally occurring, but the result of genetic engineering carried out at some point before the fall of civilisation as we know it, although the exact details of their creation are lost.

Swelling Solution

The Swelling Solution is a potion which causes whatever it touches to swell in size; its three ingredients are bat spleens, dried nettles, and puffer-fish eyes, which are carefully combined over moderate heat.

It matched by its antagonist, Deflating Draught, and each of the two substances are often employed as cures for an excess of the other.

Rumours that Swelling Solution can be used as a kind of magical viagra remain unconfirmed.

Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion & Skele-Gro.

Synergine

Synergine is a legal drug throughout the Galactic Nexus, where it is used as a combination of stimulant and painkiller.

It is particularly useful for shaking off the after-effects of stun rays (it will not revive them, however), and also as a treatment for those recently revived from cryosleep. It operates largely by assisting the body’s natural healing processes, accelerating and increasing their effects.

Synergine is particularly effective against headache symptoms, shock and most forms of nausea; it is, however, completely ineffective against the nausea caused by spacesickness.

Related drugs: Fast-Penta.

Tateen

Tateen is a mild intoxicant, mostly used by slaves on the world of Kelewan to dull the mental suffering of their servitude.

Prolonged usage of Tateen stains the teeth of users brown.

Tava

Tava is a gaseous intoxicant favoured among the kinds of people who favour such things in the Chiss Ascendancy. It is cheap and easily available in the Ascendancy, with mild doses caused inebriation and higher ones temporarily knocking out those affected.

While Tava is quick to take effect, it wears off just as quickly, with few effects remaining once the the quantity of it in the air is exhausted. For this reason, it is much-used by young Chiss students for pranks on each other, and on their more boring instructors.

Taxi

Taxi is a street drug, sold in small vials of liquid, that hit the streets of Brooklyn in 2015.

Its name derives from the fact that is yellow, and that it ‘gets you where you want to go.’ The exact properties of Taxi have rarely been detailed, but it was sold as an upper.

Related Drugs: Gigglepig and Turgidol

TC-6

One of the more effective truth drugs out there, TC-6 is typically used only by government agencies for interrogations. Administered via direct injection, it leaves those it is administered to able to respond intelligently, although it will make most people somewhat literal-minded. It will also leave them utterly without volition of their own and thus unable to lie.

It is possible to resist the effects of TC-6, although to do so requires considerable experience with truth drugs, and a certain amount of psychological conditioning, as well.

Very few people have this conditioning, however, so the drug remains useful. A single dose will last for several hours, although the drug is known to have certain side-effects regarding impaired cardiac function in some people – potentially fatal side-effects – and there is no test to determine ahead of time who will suffer them.

TD12

TD12 is a drug mostly used by dentists in England. It’s an anesthetic and sedative, which has the side effect of affecting memory formation.

This side effect makes it very interesting to a certain kind of criminal – notably, the murderer Culverton Smith once dosed some of his nearest and dearest with it so that he could tell them of his planned murder without them remembering it. Fortunately, Sherlock Holmes deduced what he had done, and Smith paid the price for his crimes.

Teamocil

There’s no I in Teamocil – at least not where you’d think…

As the name suggests, Teamocil enhances feelings of camaraderie and team spirit, although in doing so it frequently depresses the libido of users as well as causing numbness in their extremities and short term memory loss.

A product of Natural Life Food Company, Teamocil is an anti-depressant whose extreme effectiveness is unfortunately a precursor to total shut down of the pituitary gland. As of 2004, it is no longer on sale, most likely due to that side effect.

Related Drugs: Euphorazine, Profillica & Zanotab.

Terran Brandy

Terran Brandy is a potent and magical drink, an alcoholic beverage made from a distillation of the bodies of dying fae.

A green liquid that improves the ability of spell casters for a wildly variable length of time, it is considered too unreliable – and its origins too vile – to be widely used, other than by the most callous of magic users, or those that truly despise the fey races.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish and Vodare.

Thionite

A purple powder of unbelievable potency, Thionite is one the most addictive and valuable illicit drugs yet known. Paradoxically, user’s first dose is often free, since the drug is so addictive that subsequent doses can be priced at any figure the dealer chooses: the user will pay.

Thionite is so potent that a regular dose in only half a microgram. It can be snorted, swallowed, injected or even absorbed directly through the skin. While under the effects of the drug, the user has the convincing impression that their every need, want and desire is being fulfilled.

Thionite< is, unsurprisingly, illegal in almost all jurisdictions. Related Drugs: Bentlam, Fayalin, Hadive, Ladolian, Nitrolabe, Vee-Two Gas and VXN Gas.

TimeSerum

TimeSerum is derived from the venom of a now-extinct sub-species of the Gaboon Viper. Its name is something of a misnomer, as it enables one to travel through time only by that laziest of methods, suspended animation.

All known supplies of TimeSerum are under the control of members of the Rosicrucian conspiracy, stored in a vast container concealed beneath Stonehenge which is filled to a capacity equal to 200 Olympic-sized swimming pools (one of which has diving board, or so it is rumoured).

So far as is known, only two people – Alexander Pruitt and Robert Moray – have ever been dosed with it, both of them in the year 1658.

Toxin X-7

There’s little to say about Toxin X-7 that hasn’t already been covered right here. It’s a mutagen that transforms those exposed to it into brain-devouring zombies.

Were it not for the quick thinking and practicality of Ryan and Laura, you could insert your preferred zombie movie scenario here.

Fortunately, only one lab ever made Toxin X-7, and all known samples of it have been destroyed.

Of course, that just leaves the unknown ones…

Related Drugs: Turgidax

Tranquilax

Tranquilax is a stimulant, a sedative and a laxative. Produced by the Tranquilax company of Orbiston Parva, England, it is colloquially known as “the three in one.” It is sold in tablet form, and advertised as the drug to take “when life’s not worth living.”

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However, after attracting criticism from the Reverend John Smallwood, vicar of Orbiston Parva, the stock value of Tranquilax plummeted. But once Smallwood was removed, and his criticism silenced, Tranquilax was renamed Triple Crown Unction, and with a new slogan(“Builds you up; Cleans you out”) it returned to its normal sales position.

Tricetyltriparanol

Often abbreviated to TATP, Tricetyltriparanol is a simple cholesterol inhibitor, albeit is so effective at its job – and at the con-committant reduction of heart disease – that it qualifies as an anti-agathic, which is to say, it is a drug that prevents or retards aging.

Tricetyltriparanol does not actually prevent the body from forming cholesterol, but instead destroys cholesterol in the body. As such, it must be taken daily – and not at all by pregnantt women, who need a certain amount of cholesterol.

The Okie ‘Cities in Flight’ use it as part of an their immortality drug suite.

Related drugs: Ascomycin.

Tricillin PDF

Tricillin PDF is broad-spectrum abti-viral that is effective against a great number of illnesses that afflict the assorted humanoid species of the Star Trek Universe. While little has been revealed about it, it seems to be a commonly-used drug across the Federation, and its name implies that it may be an antibiotic.

The most prominent use of Tricillin PDF was during the so-called ‘Double Helix’ incidents, where the drug proved effective at slowing the effects of some strains of the ‘Double Helix”, a series of weaponized viruses. For one particular strain, it halted the progress of the disease entirely, but it was not a cure. Extensive use of Tricillin PDF was successful is prolonging the lives of many of the infected until cures could be found, however.

Triptine

Triptine is a basic legal hallucinogen with no particular distinguishing qualities.

Its name seems deliberately intended to evoke associations with LSD and other ‘trip’ drugs, but what little evidence exists suggests that it is weaker and tamer than these.

Related drugs: Skullbustium, Truth and Consequences and Yaginol.

Tripwire 7.0

A simulation of the hallucingenic experience designed for intelligent household appliances, Tripwire 7.0 is the latest in a series of such cyberdrugs.

Its popularity among sentient machines is vast, because the experience of being a household appliance, sessile constantly and unable to interact unless the humans around you decide to talk to – i.e. demand something of – you, is a spectactularly dull one.

It’s hard to blame the machines, really.

Related Drugs: Jumpstart, Mechanics and Space.

Truth or Consequences

Truth or Consequences, as the name suggests, has effects similar to the party game of the same name, with one key diffference: you can’t quit. A colourless liquid not very different from water to touch, it is often used to provoke responses that are more honest than the respondent would like.

The drug suppresses inhibitions, leading those who have taken it to speak their minds with great vehemence. As such, it is a common prank for the drug to be unknowingly administered to priests, politicians, cops and other self-appointed moral authorities. It is equally common for such pranks to end in gunfire.

Related drugs: Skullbustium, Triptine and Yaginol.

Turgidax

Turgidax promises the user an overnight tripling of penis size, which is alleged to both improve cardio-vascular health and also sexual attractiveness. You can find it here.

Likely side effects not mentioned by the advertisment include heart palpitations, heightened blood pressure, hypertension, narcolepsy, and having your penis explode like those people’s heads did in Scanners.

Related Drugs: Toxin X-7

Turgidol

Turgidol is a Canadian-made erectile dysfunction treatment. It is a prescription medicine that is made in pill form. Canadian customs takes a dim view of anyone trying to smuggle it.

Readily available in Canada and the United States, Turgidol is rumoured to provide some sort of high when taken by men who do not need it for its intended purpose, but details are understandably hard to come by.

Related Drugs: Gigglepig and Taxi

Urizen

Urizen is named for one of the gods in William Blake’s mythology for England, a deity who sought to impose reason on the world. The drug named for him was quite the reverse.

Inspired by the American “Love Bomb” experiments, Urizen was a British project (and the involvement of un-named but shadowy government agencies in its creation is confirmed) that combined the drug-based aspects of Love Bomb with advanced genetic recoding. Urizen bonded to the spinal column of users, and became a part of their DNA, where it generated hormones that would achieve aphrodisiacal submission in the user by bypassing their conscious brain entirely. However, a single dose – usually administered by injection – lasts only 14 and a half hours, and can be over-ridden by extreme pain.

Related drugs: Love Bomb

Vee-Two Gas

A highy effective muscle relaxant, usually delivered in a weaponised form, Vee-Two Gas is effective on most carbon-based lifeforms. It is mostly an inhalant – only very high quantities may be absorbed by direct skin contact.

The drug is extremely potent, and even a small quantity will cause involuntary relaxation of all voluntary muscles. It will also cause relaxation of involuntary muscles, to a lesser degree – one of the most prominent symptoms of Vee-Two Gas is the difficulty in breathing caused by relaxation of the diaphragm.

Related Drugs: Bentlam, Fayalin, Hadive, Ladolian, Nitrolabe, Thionite and VXN Gas.

Venom

One of the most addictive and dangerous of steroids, Venom first appeared on the streets of Gotham City early in the self-appointed mission of the Batman. In fact, Batman himself was one of its most prominent users for a time.

Unfortunately, in addition to enhancing strength to a superhuman degree, Venom had a number of side-effects, including muscular dystrophy (when not in use) and a capacity to addict users stronger than most drugs short of crack. Batman quickly realised this, and went cold turkey, a process that took about a month (and which was accompanied by incredible physical pain and vivid hallucinations). He never used the drug again, although villains such as Bane and Lex Luthor did.

Verbality

Verbality is one of many designer drugs developed by Orange County pharmacologist Sandy Chapman, and like most of his output, it is a colourless liquid that is taken by dropping directly into the eye.

The particular effect of Verbality is a fascination with words – their meanings, origins, sounds and so on. As such, it was dismissed by Chapman, who did not see any commercial possibilities in it – he was primarily a creator and supplier of party drugs, and a drug that his friends derisively called Verbosity did not fit his portfolio. It is a shame for Chapman that he did not see the wider possibilities – Verbality would likely have been a great hit on any university campus with strong Literature, Linguistics, Languages or Semantics faculties.

Related Drugs: Apprehension of Beauty, Buzz, California Mello, Funnybone, Get Wired, Pattern Perception & Rhinoceros

Vioplex

Vioplex is a pain killer produced by Pallogen. It is identical in formula to another drug created by Pallogen, HT1 – a drug that killed numerous test subjects by causing liver failures. Pallogen, although fully aware of the drug’s fatal nature, planned to market it anyway, since the profits to be made dwarfed any potential fine or court settlement it might cost them.

Fortunately, the involvement of the Leverage team in this case prevented the drug from ever being sold, and bankrupted Pallogen into the bargain.

Related Drugs: Fastlife

Vodare

Vodare is a drug favoured by sadists and berserkers, especially those that worship the dread god Rallaster, known variously as the Razor God, the Insane God and the God of Madmen. It is made from the crushed petals of a flower that grows only on the graves of those who dedicated their lives to the worship of Rallaster, and carries a small portion of the god’s power and nature in it.

An extremely bitter brown powder, Vodare is almost always mixed with something to sweeten it when swallowed, such as honeyed water or sweet wine. It causes it users to grow bold, arrogant and somewhat careless of danger – a state which is ideal for committing the kinds of casual murder and offhand slaughter that Rallaster likes to see as votive offerings.

Fortunately, its use is almost unknown outside of Rallaster’s small, secretive cult, and even more fortunately, the cult exists more in name than in fact, as most of those who worship Rallaster fear the discovery of their faith, and are frequently loners to boot.

Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish and Terran Brandy.

VXN Gas

VXN Gas is a weaponised drug that attacks the central nervous system. It is inhaled, and acts as a potent euphoric, inducing a sensation of pleasure and well-being that erodes willpower and leads to a semi-voluntary state of paralysis.

In fact, its euphoric effects are so strong that it is not unknown for those exposed to develop addictions to barbituates or Bentlam, as the effects of the VXN are quite pleasant to experience.

Related Drugs: Bentlam, Fayalin, Hadive, Ladolian, Nitrolabe, Thionite and Vee-Two Gas.

Weedosoros

Weedosoros is a magical poison, taught a Hogwarts School of Witchcraft and Wizardry. Little is known about it, other than that it was one of the many potions used by Severus Snape.

Related Drugs: Elixir of life and Fire Protection Potion

Wings

Wings is a cheap marketing stunt disguised as the high of tomorrow. While many of the drugs that are found in Al Amarja are unique and potent, the same is not true of Wings.

In fact, this vaunted hallucinogen is in fact nothing more than plain old LSD, dressed up with some inert chemicals and put into pill form. Pushers claim that it leads to out of the body experiences, but giving the hallucinogenic nature of the drug, this is little more than a self-fulfillling prophecy in most cases.

Particularly shady pushers of Wings will tell you that taking it with LSD heightens the experience, which is, techinically, not a lie.

Related Drugs: Blue Shock, Communion, MDA-Cubed, Nightmare, Relapse, Slo-Mo and Zorro.

Wolfsbane Potion

Wolfsbane Potion is a potion with complex and powerful magical effects. It relieves the symptoms of lycanthropy (i.e. being a werewolf). As the name suggests, the plant wolfsbane (also known as aconite and monkshood) is a major ingredient.

It is important to note that Wolfsbane Potion only relieves lycanthropic symptoms – it is not a cure, but simply reduces the pain of transformation and assists the human lycanthropy sufferer to remain mentally in control when transformed.

Wolfsbane Potion is difficult to prepare and tastes horrible, which means that few werewolves even choose to use it without a pressing need. In addition, due to the fact that aconite is a deadly poison, Wolfsbane Potion must be prepared very carefully – too much aconite in the mixture will permanently cure the imbiber of lycanthropy – and life.

Related drugs: Confusing Concoction, Rat Tonic and Shrinking Solution.

X-Drugs

X-Drugs are like a stronger form of LSD. So strong, in fact, that they grant the user a certain amount of superpowers – including telekinesis, teleportation, intangebility, reversal of personal gravity and super-speed – while they last. A standard dose lasts a short time – an hour or so – and reportedly, the experience is quite a rush. Despite the name, there is in fact only one X-Drug, although it is often tailored to the DNA of the user for maximum effectiveness.

The principle by which X-Drugs operate is based on an unusual interpretation of certain aspects of quantum physics, notably Heisenberg’s Uncertainty Principle. They allow the user to make the apparent manipulation of reality by consciousness under LSD to be an actual manipulation, albeit of a strongly limited nature.

X-Drugs were created by an unamed former faculty member at UC Berkeley, and later improved by both the Scary Clowns and their enemies, the Troop.

No, actually, all of the above is a lie: there are no X-Drugs: they are fictional even in the context of the fiction in which they appear, and their effects were simulated by the Scary Clowns for their own purposes.

X-13

X-13 is a short-term memory erasing drug. It causes limited amnesia, typically for a period of about 24 hours. The amnesia it induces can be defeated by hypnotic recall sessions, and it is known to be diminished in effectiveness if the subject’s bloodstream has a high alcohol level.

It is applied as an aerosol spray, and tends to knock out the subject upon application, generally for a period of several hours. X-13‘s very existence is a classified secret, and it is available only to agents of the NSA and CIA, although stocks do occasionally turn up on the black market.

Xenite

A highly dangerous and radioactive drug, Xenite is not native to the world of Top Ten (and America’s Best Comics in general). It is an element from a different periodic table, specifically that of Grand Central, the parallel universe of Precinct 1.

Given its nature, there are very few people who can use it without suffering radiation poisoning, all of them superhuman or divine in nature. The only known user of the drug at this time is Commisioner Ultima, of Grand Central, whose power levels were akin to those of Superman. As she is now deceased, the origins and history of the drug may never be known.

In effect, the drug appeared to be a form of super-powered heroin, although given that the only depiction of its use was a deliberate overdose, it is hard to be certain of this identification.

Related drugs: Amazo Pills,