Little is known about Amazo Pills other than the name. Certain inferences can be be made based on it, however.
Amazo Pills are named after an android created by one Professor Ivo, which was able to duplicate all the superhuman abilities of the Justice League of America.
It is likely, therefore, that the pills duplicate this effect to some extent, and presumably allow the user to duplicate the powers of nearby superhumans. Amazo himself was able to duplicate even powers granted by artifacts such as Green Lantern’s ring or Wonder Woman’s lasso – it is unlikely that the drug is anywhere near this powerful.
Related drugs: Darkshots, Hyperdrene, Mongoose Blood and Xenite
Batch 5 is a particular formulation in a series of mixtures of Pituarin and Pinearin. The exact quantities of each, and any other possible ingredients, are not known. A potent and unpredictable mutagen, it was administered to several inmates at the Larkhill Resettlement Camp during 1993.
While the effects of Batches 1 through 4 are unknown, Batch 5 frequently caused the development of supernumary organs in those it was administered to, often accompanied by the atrophy of other organs. It was regarded as a success by the researchers and administration of Larkhill, although those it was administered to were not volunteers and gave no consent to be experimented on, and most of them died in agony.
In at least once case, that of the individual known only as “Codename V”, Batch 5 seems to have caused no deleterious physical effects, instead apparently enhancing strength and agility, although it is possible that the drug did drive “V” mad – or perhaps madder, as “V” may have already been insane at the time he was dosed.
No known samples of Batch 5 or instructions for its preparation survived the destruction of the Larkhill camp by “Codename V”.
An alchemical concoction masquerading as a craft beer, Black Frost was briefly on sale at one particular bar on the Sunnydale campus of the University of California.
Repeated doses of Black Frost will lead to the imbiber reverting to a caveman-like level of intelligence, closely followed by physical mutations to match. Understandably, the user rarely realises that they have been dosed before it’s too late for them to realise much of anything.
It’s mostly used to get even with smart-ass college kids.
Related Drugs: Calendula, Calynthia Powder, Gill Man DNA and Orpheus.
In September 1967, Blue Sunshine was created in a lab at Stanford. It was a variant of LSD, used by a number of members of the graduating class of that year.
In 1978, a previously unknown set of side effects to Blue Sunshine use became apparent: it caused swift hair loss, inhuman strength and murderous psychotic episodes in several users. Medical study of one of them showed severe chromosonal damage resulting from the drug’s use. An investigation conducted by the FDA located some but not all of the former users of the drug, with a total of 255 doses remaining unaccounted for.
Originally developed by Banner Value Drug and Vitamin Laboratories, Inc. as a cure for nerve damage, intended to stimulate the growth of damaged nerves, Cerebrocreatine was a failure in that goal, but worked very well in enhancing the development of neural pathways in the brain. Unfortunately, the side effect of these little yellow pills tended to be a fascination with knowledge for its own sake, a penchant for grandiose experimentation and marked tendency towards pednatry.
Cerebrocreatine is one of the few drugs in history to have had its own antidote – marketed as Super-Aktion – developed by the same company that created it, although like Cerebrocreatine, the antidote too was also too strong…
Related Drugs: De-Tox, Nullergin-200 and Super-Aktion
Created by Dr Michael Grant, a Washington DC based scientist, the original purposes of Cortexin was lost to history – along with its creator and all his notes – when a nuclear war broke out. Grant’s test animals, who had been injected with the drug, escaped in the course of the devastation that followed.
It was at this point that what was presumably an unintended side effect, the animals dosed with Cortexin proved to been altered on a genetic level. Over the course of several generations, they developed greater intelligence, bipedal locomotion, hands with opposable thumbs, and even the power of speech.
A variety of species were used by Grant in his experiments, including apes, bats, dogs, gophers, leopards, lions, pumas, rats, sloths, tigers and wolves. The wide range of species, and the fact that each of them had a large enough population to be able to breed viably, along with the location of Grant’s researches, strongly suggests that his experiments were funded by the Pentagon.
NB: there is no known connection between this Cortexin and the real world drug of the same name.
The Deflating Draught is probably best known as an antidote to the Swelling Solution. As such, it is a standard medical treatment in the wizarding world, used to reduce swellings of all kinds, whether they are magically induced or not.
Rumours that it can be used as a kind of magical viagra remain unconfirmed.
Related Drugs: Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.
A street drug developed by the very people who are charged with policing it, Dust is a red powder that stimulates telepathic powers in humans (and some other species) for the duration of its use.
Dust was created by the Psi-Corps in an effort to create more human telepaths. It has been an unmitigated failure in that respect, and remains potentially a huge embarassment to the Psi-Corps should its origins become public. In the meantime, the same people who created the drug have the job of hunting down and punishing those who use it.
The fact that the drug works on non-human races, notably the Narn, is most likely indicative of the genetic meddling of the Vorlons with these races, with the drug tapping the telepathic genes implanted by that race.
Related drugs: Psi-blockers
It’s somewhat unclear whether Ent-Draughts are some form of enchanted juice or some form of enchanted water. Certainly it is loved by Ents, as Treebeard keeps a supply laid in. But what is most attention-grabbing about this liquid the effect that it has on hobbits.
Even a single draught will cause feelings of extreme well-being and act as a restorative to good health and boundless energy.
In the cases of Merry and Pippin, it even caused them to grow a considerable amount, making them two of the tallest hobbits ever. Presumably, it would have analogous effects on humans, although thiis has never been tested – and the only species to drink Ent-Draughts are the Ents themselves. The effect it has on them is unclear, although it is implied to be a mild intoxicant.
Related drugs: Athelas, Miruvóre and Pipe-Weed
The true nature and origin of Eucharist is a closely guarded secret in the Empire of Golgoth. In fact, only he (and a few lieutenants whose curiosity exceeded their loyalty) know how the drug is made.
Eucharist is a highly addictive stimulant (possibly even at mutagenic levels) and euphoric, described by its users as better than sex (although not, apparently, better than sex and Eucharist combined), although its effects wear off in time. Golgoth gives it only to his most trusted inner circle as a means of both empowering them and ensuring their loyalty – and even then, only once a month. It is generally in the form of standard sized capsules, red and white in colour. It is unclear if anyone has ever survived withdrawal from it, but it is widely agreed that going cold turky from it is a terrible physical and emotional ordeal.
The true secret of Eucharist is perhaps the only thing about it that is more horrific than withdrawing from it would be: it is in fact the unprocessed blood of an alien superhero named Endymion, who came to Earth with powers and abilities far beyond those of mortal men… and who was defeated, imprisoned and used as a source of Eucharist by Golgoth.
Glass-like shards that are the remains of windows and glassware from cities that have been destroyed by Chaos far in the grim dark future of Warhammer 40,000, Flects are powerfully addictive hallucinogens. Gazing into them causes visions, although repeated use seems to trigger mutagenic effects as well.
Flects are profoundly illegal in the Imperium. The Inquisition ceaselessly hunts both those who use and those who sell the drug, and not without good reason: the visions and mutations are gifts of Chaos, and Chaos does not give gifts for any reason other than to advance the cause of Chaos.
FX7 is an extremely powerful mutagen, created by Carrick Masterson by extensively by modifying the psychedelic Tryptamine 5-MEO-DIPT in San Francisco in the mid- to late Sixties. He created it as a way to form his own superhuman group, originally called the Levellers, later re-named the Front Line.
However, the effects of FX7 vary wildly from person to person – Masterson refers to the process as ‘tuning’, and even the doses and methods of administration vary based on each subject’s medical work up. Although only one dose is required, to actually make it kick in takes a high level of adrenalin response: a shock or fright. When that happens, the subject can expect 12 hours of horribly mutating pain, after which they will wake up with superpowers.
Giagra was sold through classified ads in some of the more dubious porn magazines. It was a penis enlarging drug that not only lacked FDA approval but actually boasted about the fact in its advertisements. Unsurprisingly, this led the FDA to raid the headquarters of Dopecom, manufacturers of Giagra, and shut them down.
The recommended dose is a quarter ounce a day. Exceeding the recommended daily dose of Giagra can cause side effects such as heart palpitations and blurred vision. A young man named Richard Head broke into the Dopeco factory and was mutated into a human-sized and -shaped penis capable of ejaculating through the hole on the top of his head after falling into a vat of Giagra. He became a supervillain under the name Dick Head.
Gill Man DNA is a powerful mutagen that is incorrectly believed by its creator to be a steroid.
Ingested in the form of steam, Gill Man DNA is derived from mutated fish DNA, itself engineered from several different fish species and then further warped by exposure to the magical energies of the Sunnydale Hellmouth.
Although it does increase the swimming abilities of those who take it, the manner in which this is achieved is by slowly mutating them into amphibious fishlike humanoids (it is not clear whether they can breathe underwater as well as in the open air).
Related Drugs: Black Frost, Calendula, Calynthia Powder and Orpheus.
Few details are known about Hair-Raising Potion. As the name suggests, the potion causes the imbiber’s hair to stand on end. That’s about it.
Oh, and one of the ingredients is an unspecified number of rat tails. No one knows why, and we’re all happier that way.
Related Drugs: Deflating Draught, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.
Kick is the street name of the drug Hypercortisone D – but it’s really a sentient bacterium that more often goes by the name Sublime.
Native to the Marvel Universe, Kick appears to cause psychosis, but this is actually the result of it enabling Sublime to control the minds of whoever takes it – a list which includes Kid Omega, Beast and Magneto (or possibly Xorn – accounts vary). In at least one alternate future, this drug/entity actually succeeded in taking over the world, which is a rare accomplishment for any drug to claim.
Sublime/Kick has few discernable goals, but one of them is the absolute destruction of mutantkind, which it regards as one of the few threats to its existence – largely because it can control mutants only when they take it in Kick, rather than the purely viral control that is sufficient to control most humans.
Krotan is a potent short term mutagen, which allows complete shape-shifting for the user. It was at one time quite popular amongst the upper classes of Thanagar – although it appears to have also worked for a variety of other alien races.
The primary Krotan dealer on Thanagar was Byth – who was also the head cop, so there was a slight conflict of interest. Eventually, Byth was overthrown and fled to Earth, now hopelessly addicted to Krotan – maddened both by the drug itself (seems his brain never uite made it back to its original shape) and by his subsequent withdrawal from it.
Lot Six was the sixth in a series of mild hallucinogen that it was hoped would induce extrasensory perception in its users. Glorying in the scientific name of di-lysergic triune acid, it was nicknamed “booster acid” by the team that developed it at the behest of the Shop, a shadowy covert agency of the US government about which little is known.
A dozen subjects participated in the tests of Lot Six in 1969. Most of them died or went insane, but two of them, Andrew McGee (who developed minor coercive telepathic abilities) and Victoria Tomlinson (who developed an even smaller telekinetic talent) escaped from the Shop and spent many years on the run from it. After their marriage and the birth of their daughter Charlie, they discovered that a side effect of Lot Six was chromosomal mutation. Charlie developed a major pyrokinetic talent, which she used to destroy a Shop installation. Later, she brought the story of Lot Six to Rolling Stone Magazine, who created a minor scandal when the published it in 1980 (which was unfortunately quickly pushed from the front pages by the hostage situation at the US embassy in Tehran and the Presidential campaign).
Mandrake Restorative Draught is cure for various magical curses and transfigurations.
One of its best known uses is to cure the victims of basilisk attacks, a use to which it was put to cure the several victims of such attacks at Hogwarts across 2002 and 2003. Mandrake Restorative Draught is unusual in that it equally efficacious when administered to ghosts as to the living.
Related Drugs: Deflating Draught, Hair Raising Potion, Pepperup Potion, Polyjuice Potion, Skele-Gro & Swelling Solution.r of Secrets (First mentioned)
A rare cyberdrug that affects both machines and people, Mechanics is a hard drug to quantify. It is slow to build into an addiction, but irreversible in its effects long before that point.
Mechanics can only be taken by a human and an artificial intelligence in tandem – it is a source code level drug that rewrites the source code of those who take it. For a human, that means DNA.
Each use of the drug transforms a little more of the user’s body into inorganic matter, slowly transforming them into a cyborg at first, and later, an artificial intelligence altogether. The high from taking the drug might fade away, but the mutations never do.
Related Drugs: Jumpstart, Space and Tripwire 7.0.
Originally a powerful, non-addictive mutagen devised by X-Man Hank McCoy (a.k.a. The Beast), Mutant Growth Hormone has since been debased into a less potent but more addictive form, and shown up on the streets of New York City, usually abbreviated to MGH.
MGH is created from the DNA of a mutant (or mutate), and grants the user with limited superpowers for a brief period. Although most sellers of the drug claim that the powers granted are related to the person who the MGH was harvested from, this is in fact untrue, and the powers granted arise from the activation of latent mutant genes in the user.
Known DNA sources for MGH include Hank McCoy (who made the original formulation from his own DNA and took it himself, which may account for both the potency and permanency of the effects), Leland Owlsley (the criminal known as The Owl) and Mattie Franklin (the third Spider-Woman). No verified sample has ever been created from the DNA of Peter Parker (Spider-Man) although dealers frequently claim him as a source of the drug.
NEURO is an intelligence-enhancing drug, but is unclear exactly how it works – it may be a mutagen, a stimulant or a psychiatric, or some combination of these or other elements.
Questions of mechanism aside, the drug is known to be very effective.
NEURO is known to exist in most of a cluster of closely-related alternate timelines or eigenstates.
Related drugs: Ex-Tend, FEMFREE, FOREVER and ORGASMOR.
Possibly the most powerful mutagen ever created, the Nuncio (Latin for ‘messenger’) was created by Dr Richard Fletcher in the late Sixties, in a private lab funded by Randolph Jaffe in Baja California, on the coast of the Pacific.
There are two versions of the drug, the lesser being a prototype that was tested on an ape named Raul and evolved him to more human state, making him sentient and capable of human speech. The completed Nuncio was a bluish serum that was known to move under its own power in search of a host.
The effects of the serum varied from person to person, but were always strongly reflective of the mental states of those who took it. Inevitably, it would grant them a degree of mystical power, including the ability to see and travel beyond our mundane reality to more fundamental ones. Three doses were made, and a total of five people are known to have taken the Nuncio: Fletcher and Jaffe, who each took a full dose, while the remaining dose was shared between Jaffe’s son Tommy, a woman named Tesla Bombeck and the ape-man Raul.
A mysterious and deadly substance, Ortho Orange #42 has been illegally dumped by an un-named American corporation in at least one vacant lot, possibly in Philadelphia. Little is known of its chemical composition or intended use, but its effects on both human and canine subjects are well-documented.
One human subject, “Scotty”, developed a blood-clotting disorder as a result of his exposure, in addition to his skin turning green, losing his sight, and requiring nasal tubes to breathe. At this point, barring a miracle, his prognosis is terminal. A canine subject experienced less dramatic effects, although his once grey fur was changed to a yellow shade by exposure to the same substance.
Polyjuice Potion is an alchemical preparation that allows a human drinker to temporarily assume the form of another person – although only a particular person. In particular, it cannot be used to take the form of any non-human – although numerous attempts have ended in the potion drinker being stuck in some sort of in-between form.
The potion is a difficult and time-consuming one to prepare – among other things, it needs to brew for a month after its final brewing – and one of the most difficult to acquire ingredients is a sample of the target person, usually hair, although other substances will work just as well. Polyjuice Potion is also highly variable in the duration of its effect, with the quality of the numerous ingredients and the skill of the brewing both influencing the outcomes.
Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Skele-Gro & Swelling Solution.
A hair growth drug that was later banned by the FDA, Profillica actually did have some positive effects of hair growth, albeit not always on the top of the head.
It was banned as a result of its negative effects on the central nervous system (it frequently causes uncontrollable spasming). Profillica is widely believed to be made from monkey hormones, but the truth of this assertion is unknown.
Related Drugs: Euphorazine, Teamocil & Zanotab.
A perfectly legal drug developed by the Psi-Corps in order to suppress the telepathy of those psis who do not wish to join the Psi-Corps.
Psi-blockers take about three hours to take effect after they are administered (via direct injection), although the dosage size seems to affect how long they last for – a standard dose for a registered telepath lasts for a week. Unfortunately, doses that large have the unfortunate side effect of causing depression in long term users (although sociopaths seem immune from this effect).
Related drugs: Dust.
PX-41 is a potent mutagen created by the supervillain El Macho. It turns anyone injected with it into an giant white-haired purple rage monster, whether they’re an articially created life form or a dangerous Mexican supervillain.
Both PX-41 and its antidote were created by Dr. Nefario, an elderly British mad scientist in the employ of El Macho (although he betrayed him to create the antidote). All known samples are nor presumably in the custody of the Anti-Villain League, although Dr. Nefario could no doubt whip up more easily enough.
A bright yellow powder ingested directly, Rapture is taken as a party drug, but has the unusual effect of increasing the cognitive power of its users, especially with regard to mathematical calculations. Even a single dose seems to have this effect.
It also creates limited psychic powers, including the ability to psychically attack others, and also creates a limited mindlink between users – a mindlink that can be used to increase the power of the psychic attacks. The mindlink allows access to memories and also the ability for the most heavy users to control the less heavy, effectively over-writing their minds and using them to increase the power of their own mental powers.
It is also powerfully addictive – a single hit is enough to get a user hooked. It was created by a sentient AI, with the intention of controlling humans. Fortunately, it had but one source, a young chemist in Texas who committed suicide while under the effects of the drug. It appears that the effects are temporary, and wear off when the drug is no longer consumed.
Rat tonic is a healing potion for specifically intended to heal rats. It can also be used to treat the symptoms of ageing in rats. It is sold in a small red bottle at the Magical Menagerie in Diagon Alley, and presumably at similar locations elsewhere.
It is also the case that excessive use of Rat tonic can result in the rat drinking it becoming engorged, enlarged and even deformed. It is recommended that the directions on the bottle be followed to the letter.
Related drugs: Confusing Concoction, Shrinking Solution and Wolfsbane Potion.
An unlikely chemical capable of tapping into that same power that caused the Ten Plagues of Egypt – i.e. the Wrath of God – Sentry Serum was created by a un-named Professor in an attempt to recreate the Super Soldier Serum.
Clearly, he succeeded beyond his wildest dreams. Just as clearly, the addict and thief who took the sole, untested sample of the serum, Robert Reynolds, was manifestly unsuited for the nigh-infinite power it unleashed in him.
It is unclear whether the serum caused his multiple personalities, or merely exacerbated an existing tendency in Reynolds, but in either identity – the ‘heroic’ Sentry or the evil ‘Void’ – he had more power than he could easily control. With his death, it is unlikely that the serum will ever be recreated.
Shrinking Solution is, as the name suggests, a potion that causes the drinker to shrink. It is primarily used to transport livestock.
However, the potion does not merely cause shrinking, but also causes the imbiber to become younger (which often also results in a loss of size, if the reversion continues into childhood). As a result, it must be used with great care.
Related drugs: Confusing Concoction, Rat Tonic and Wolfsbane Potion.
Perhaps more indicative of the insanity of the Joker than anything else about him, Smilex is a deadly poison that causes horrific facial deformations, usually in form of a rictus grin.
Smilex is made in both liquid and gaseous forms – the gas resembles a green smoke. The liquid can be mixed into almost any foodstuffs.
The puzzling thing about Smilex is the business plan behind its distribution. The Joker gives it away, seeking the widest possible range of people in Gotham, with the intent of killing them. Surely, this is insanity by any modern standard: the total absence of anything even resembling a profit motive – in fact, the Joker probably took a loss on the deal.
An extremely potent mutagen, Strim is the drug of choice in Turn Neighbourhood, the hardest and weirdest place in the entire City. It wreaks havoc on the user’s DNA, deranges their perceptions into what can only be described as an alien state (no two alike, yet) and largely as a result of the foregoing, kills a hell of a lot its users.
Its only practical use is to transform one’s DNA so thoroughly that DNA-coded poisons and such will no longer recognize the user as their target – a highly specialised and largely criminal endeavour.
Related Drugs: Dilligenz, Dopaz and Jahavan coffee
The Swelling Solution is a potion which causes whatever it touches to swell in size; its three ingredients are bat spleens, dried nettles, and puffer-fish eyes, which are carefully combined over moderate heat.
It matched by its antagonist, Deflating Draught, and each of the two substances are often employed as cures for an excess of the other.
Rumours that Swelling Solution can be used as a kind of magical viagra remain unconfirmed.
Related Drugs: Deflating Draught, Hair Raising Potion, Mandrake Restorative Draught, Pepperup Potion, Polyjuice Potion & Skele-Gro.
Terran Brandy is a potent and magical drink, an alcoholic beverage made from a distillation of the bodies of dying fae.
A green liquid that improves the ability of spell casters for a wildly variable length of time, it is considered too unreliable – and its origins too vile – to be widely used, other than by the most callous of magic users, or those that truly despise the fey races.
Related Drugs: Agony, Baccaran, Devilweed, Luhix, Mordayn Vapor, Mushroom Powder, Redflower Leaves, Sannish and Vodare.
TimeSerum is derived from the venom of a now-extinct sub-species of the Gaboon Viper. Its name is something of a misnomer, as it enables one to travel through time only by that laziest of methods, suspended animation.
All known supplies of TimeSerum are under the control of members of the Rosicrucian conspiracy, stored in a vast container concealed beneath Stonehenge which is filled to a capacity equal to 200 Olympic-sized swimming pools (one of which has diving board, or so it is rumoured).
So far as is known, only two people – Alexander Pruitt and Robert Moray – have ever been dosed with it, both of them in the year 1658.
There’s little to say about Toxin X-7 that hasn’t already been covered right here. It’s a mutagen that transforms those exposed to it into brain-devouring zombies.
Were it not for the quick thinking and practicality of Ryan and Laura, you could insert your preferred zombie movie scenario here.
Fortunately, only one lab ever made Toxin X-7, and all known samples of it have been destroyed.
Of course, that just leaves the unknown ones…
Related Drugs: Turgidax
X-Drugs are like a stronger form of LSD. So strong, in fact, that they grant the user a certain amount of superpowers – including telekinesis, teleportation, intangebility, reversal of personal gravity and super-speed – while they last. A standard dose lasts a short time – an hour or so – and reportedly, the experience is quite a rush. Despite the name, there is in fact only one X-Drug, although it is often tailored to the DNA of the user for maximum effectiveness.
The principle by which X-Drugs operate is based on an unusual interpretation of certain aspects of quantum physics, notably Heisenberg’s Uncertainty Principle. They allow the user to make the apparent manipulation of reality by consciousness under LSD to be an actual manipulation, albeit of a strongly limited nature.
X-Drugs were created by an unamed former faculty member at UC Berkeley, and later improved by both the Scary Clowns and their enemies, the Troop.
No, actually, all of the above is a lie: there are no X-Drugs: they are fictional even in the context of the fiction in which they appear, and their effects were simulated by the Scary Clowns for their own purposes.
Xperience is a tailored gene-therapy, consumed as a drug in aerosolised form via an inhaler. It is a product of the Sublime Corporation, created from the genetic material of assorted mutants, mostly members of the X-Men (since they have the highest media profile and Sublime intends to market the drug).
A brief snort of Xperience will power up the user with the powers of the X-Man in question for several hours. It appears to be mildly addictive, although it is unclear whether this is a physical effect or merely a psychological one.
Known members of the X-Men whose genetic material was used to create varieties of Xperience include Wolverine, Deadpool, Cyclops, Beast, Iceman, Angel, Emma Frost, Professor X and Jean Grey in both her Marvel Girl and Phoenix incarnations. (But not Adam X. Never Adam X.) However, due to the efforts of the X-Men, Xperience is no longer being created, and only a few stolen samples of it still exist.